Messina Leonardo, Giardi Maria Teresa
Microsis srl, Via degli Olmetti, 8a, 00060 Formello, Italy.
Institute of Cristallography, CNR Area of Research of Rome, 00010 Rome, Italy.
Biosensors (Basel). 2024 Dec 24;15(1):3. doi: 10.3390/bios15010003.
Recent studies have shown that lactate is a molecule that plays an indispensable role in various physiological cellular processes, such as energy metabolism and signal transductions related to immune and inflammatory processes. For these reasons, interest in its detection using biosensors for non-invasive analyses of sweat during sports activity and in clinical reasons assessments has increased. In this minireview, an in-depth study was carried out on biosensors that exploited using electrochemical methods and innovative nanomaterials for lactate detection in sweat. This detection of lactate by biosensors in the sweat method seems to be feasible and highly desirable. From this commentary analysis, we can conclude that the correlation between lactate concentrations in sweat and blood is not yet clear, and studies are needed to clarify some key issues essential for the future application of this technology.
最近的研究表明，乳酸是一种在各种生理细胞过程中发挥不可或缺作用的分子，例如与免疫和炎症过程相关的能量代谢和信号转导。基于这些原因，人们对使用生物传感器在体育活动期间对汗液进行无创分析以及在临床诊断中检测乳酸的兴趣有所增加。在这篇综述中，对利用电化学方法和创新纳米材料检测汗液中乳酸的生物传感器进行了深入研究。通过生物传感器以汗液检测乳酸的方法似乎是可行且非常有必要的。从这篇评论分析中，我们可以得出结论，汗液和血液中乳酸浓度之间的相关性尚不清楚，需要开展研究以阐明这项技术未来应用所必需的一些关键问题。
