Casagrande Maria, Forte Giuseppe, Favieri Francesca, Mingarelli Alessandro, Agostini Francesca, Arcari Luca, Passaseo Ilaria, Semeraro Raffaella, Camastra Giovanni, Langher Viviana, Cacciotti Luca
Dipartimento di Psicologia Dinamica, Clinica e Salute, Università di Roma "Sapienza", Via Degli Apuli 1, 00185 Roma, Italy.
Dipartimento di Psicologia, Università di Roma "Sapienza", Via dei Marsi 78, 00185 Roma, Italy.
J Pers Med. 2024 Dec 27;15(1):6. doi: 10.3390/jpm15010006.
: Takotsubo syndrome (TTS) shares many clinical features with acute myocardial infarction (AMI); however, its underlying pathophysiology remains elusive due to specific characteristics (i.e., reversibility, presence of stressors, and low mortality rate). Emerging evidence suggests that TTS often emerges following significant somatic, emotional, or psychological stressors. Several studies have investigated the biological factors that may contribute to the onset of TTS, including the release of stress hormones. However, the psychological characteristics associated with TTS, which may be useful for differentiating TTS from other cardiovascular conditions, remain poorly explored. This study aims to overcome these limitations by evaluating whether certain psychological features may allow this specific clinical condition to be differentiated from other cardiovascular conditions. : This study compared three groups of individuals: patients with TTS (N = 56), patients with AMI (N = 52), and individuals without a history of cardiovascular disease (N = 56). Patients were examined three months after the acute phases. The objective was to identify and examine multiple psychological factors involved in TTS, including state and trait anxiety, symptoms of depression, psychological symptoms, distress, perceived social support, and health locus of control. : The results indicate that patients with TTS exhibited higher levels of somatization, trait anxiety, obsessive-compulsiveness, and overall psychological distress than patients with AMI and control groups. These findings were associated with an internal health locus of control and low-risk lifestyles. : This psychological exploration of TTS reveals a multifaceted relationship between the mind and the heart, challenging traditional notions of cardiovascular pathophysiology and suggesting the importance of considering the cardio-psychological health of patients in both preventive and intervention programs.
应激性心肌病（TTS）与急性心肌梗死（AMI）有许多共同的临床特征；然而，由于其特定特征（即可逆性、存在应激源和低死亡率），其潜在的病理生理学仍不清楚。新出现的证据表明，TTS通常在重大的躯体、情绪或心理应激源之后出现。几项研究调查了可能导致TTS发病的生物学因素，包括应激激素的释放。然而，与TTS相关的心理特征，这可能有助于将TTS与其他心血管疾病区分开来，仍未得到充分探索。本研究旨在通过评估某些心理特征是否可以将这种特定的临床状况与其他心血管疾病区分开来，来克服这些局限性。：本研究比较了三组个体：TTS患者（N = 56）、AMI患者（N = 52）和无心血管疾病史的个体（N = 56）。在急性期三个月后对患者进行检查。目的是识别和检查与TTS相关的多种心理因素，包括状态焦虑和特质焦虑、抑郁症状、心理症状、痛苦、感知到的社会支持以及健康控制点。：结果表明，与AMI患者和对照组相比，TTS患者表现出更高水平的躯体化、特质焦虑、强迫观念和总体心理痛苦。这些发现与内部控制点和低风险生活方式有关。：对TTS的这种心理探索揭示了身心之间多方面的关系，挑战了心血管病理生理学的传统观念，并表明在预防和干预计划中考虑患者的心脏心理健康的重要性。
