Casagrande Maria, Forte Giuseppe, Favieri Francesca, Agostini Francesca, Giovannoli Jasmine, Arcari Luca, Passaseo Ilaria, Semeraro Raffaella, Camastra Giovanni, Langher Viviana, Pazzaglia Mariella, Cacciotti Luca
Dipartimento di Psicologia Dinamica, Clinica e Salute, Università di Roma "Sapienza", Via Degli Apuli 1, 00185 Roma, Italy.
Dipartimento di Psicologia, Università di Roma "Sapienza", Via dei Marsi 78, 00185 Roma, Italy.
J Clin Med. 2021 Oct 26;10(21):4940. doi: 10.3390/jcm10214940.
The onset of Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is thought to be associated with some life events. This study focuses on clarifying life event characteristics and the role of triggers in the onset of TTS. Participants with TTS ( = 54) were compared to those with acute myocardial infarction (AMI; = 52) and healthy individuals ( = 54). Using a modified version of the Interview for Recent Life Events, information about general life events perceived as stressful and triggers preceding the onset of a cardiac syndrome was collected. The assessment included the impact of these events as indicated by the participants and estimated by the interviewer; finally, the objective impact was considered. Although the number of events and the objective impact did not differ among the groups, patients with TTS reported a more negative perceived impact. Moreover, 61% of these patients objectively and subjectively reported a more stressful trigger before the onset of the disease (in the 24 h preceding the cardiac event) than those reported by patients with AMI. The dynamic between life events and individual responses could help differentiate TTS from other cardiovascular events, such as AMI. This study suggests that patients' perception of some life events (whether triggers or general life events) could represent a possible marker of TTS.
应激性心肌病（Takotsubo综合征，TTS）的发病被认为与某些生活事件有关。本研究旨在明确生活事件特征以及触发因素在TTS发病中的作用。将TTS患者（n = 54）与急性心肌梗死（AMI；n = 52）患者及健康个体（n = 54）进行比较。使用经过修改的近期生活事件访谈表，收集有关被视为有压力的一般生活事件以及心脏综合征发作前触发因素的信息。评估内容包括参与者指出并由访谈者估算的这些事件的影响；最后，考虑客观影响。尽管各组间事件数量和客观影响并无差异，但TTS患者报告的感知影响更为负面。此外，这些患者中有61%客观和主观地报告，在疾病发作前（心脏事件前24小时内）的触发因素比AMI患者报告的更具压力。生活事件与个体反应之间的动态关系有助于将TTS与其他心血管事件（如AMI）区分开来。本研究表明，患者对某些生活事件（无论是触发因素还是一般生活事件）的感知可能是TTS的一个潜在标志物。
