Guarnieri Gianluca, Conte Edoardo, Marchetti Davide, Schillaci Matteo, Melotti Eleonora, Provera Andrea, Doldi Marco, Squeo Maria Rosaria, Pelliccia Antonio, Maestrini Viviana, Andreini Daniele
Department of Biomedical and Clinical Sciences, University of Milan, 20122 Milan, Italy.
Division of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, 20157 Milan, Italy.
J Cardiovasc Dev Dis. 2024 Dec 31;12(1):13. doi: 10.3390/jcdd12010013.
Congenital coronary artery anomalies (CAAs) are a significant cause of sudden cardiac death and a key factor in determining athletes' eligibility for competitive sports. Their prevalence varies with diagnostic modalities and may present as asymptomatic or with life-threatening ischemic or arrhythmic events. This case series highlights the diverse manifestations of CAAs and the clinical approaches used to determine sports eligibility.
Five competitive athletes with different CAAs are presented. These cases include anomalous coronary origins, intramyocardial bridges, and coronary fistulas. Diagnostic tools, including coronary CT angiography (CCTA), cardiac magnetic resonance imaging (CMR), and stress tests, were essential in evaluating these anomalies and determining treatment strategies. In some cases, such as intramyocardial bridges, surgical intervention was necessary, while others required conservative management or exclusion from competitive sports.
CAAs require individualized care based on risk stratification through advanced imaging techniques and functional assessment. Surgical interventions are reserved for high-risk anomalies, while others may be managed conservatively. Early detection and tailored management are crucial for ensuring athletes' safety, and ongoing research is needed to optimize long-term outcomes.
先天性冠状动脉异常(CAA)是心源性猝死的重要原因,也是决定运动员参加竞技运动资格的关键因素。其患病率因诊断方式而异,可表现为无症状,或出现危及生命的缺血性或心律失常事件。本病例系列突出了CAA的多样表现以及用于确定运动资格的临床方法。
介绍了5例患有不同CAA的竞技运动员。这些病例包括冠状动脉起源异常、心肌桥和冠状动脉瘘。诊断工具,包括冠状动脉CT血管造影(CCTA)、心脏磁共振成像(CMR)和负荷试验,对于评估这些异常情况和确定治疗策略至关重要。在某些情况下,如心肌桥,需要进行手术干预,而其他情况则需要保守治疗或禁止参加竞技运动。
CAA需要通过先进的成像技术和功能评估进行风险分层,从而提供个体化治疗。手术干预仅适用于高危异常情况,其他情况可进行保守治疗。早期检测和针对性管理对于确保运动员的安全至关重要,需要持续开展研究以优化长期治疗效果。