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掺入牙本质黏结剂中的溶胶-凝胶法制备生物活性玻璃的体外比较研究:对牙本质再矿化和力学性能的影响

Comparative In Vitro Study of Sol-Gel-Derived Bioactive Glasses Incorporated into Dentin Adhesives: Effects on Remineralization and Mechanical Properties of Dentin.

作者信息

Park In-Seong, Kim Hyun-Jung, Kwon Jiyoung, Kim Duck-Su

机构信息

Department of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul 02447, Republic of Korea.

Department of Conservative Dentistry, Kyung Hee University Dental Hospital, Seoul 02447, Republic of Korea.

出版信息

J Funct Biomater. 2025 Jan 16;16(1):29. doi: 10.3390/jfb16010029.

Abstract

To overcome limitations of dentin bonding due to collagen degradation at a bonded interface, incorporating bioactive glass (BAG) into dentin adhesives has been proposed to enhance remineralization and improve bonding durability. This study evaluated sol-gel-derived BAGs (BAG79, BAG87, BAG91, and BAG79F) and conventional melt-quenched BAG (BAG45) incorporated into dentin adhesive to assess their remineralization and mechanical properties. The BAGs were characterized by using field-emission scanning electron microscopy (FE-SEM) and transmission electron microscopy for surface morphology. The surface area was measured by the Brunauer-Emmett-Teller method. X-ray diffraction (XRD) analysis was performed to determine the crystalline structure of the BAGs. Adhesive surface analysis was performed after approximating each experimental dentin adhesive and demineralized dentin by using FE-SEM. The elastic modulus of the treated dentin was measured after BAG-containing dentin adhesive application. The sol-gel-derived BAGs exhibited larger surface areas (by 400-600 times) than conventional BAG, with BAG87 displaying the largest surface area. XRD analysis indicated more pronounced and rapid formation of hydroxyapatite in the sol-gel BAGs. Dentin with BAG87-containing adhesive exhibited the highest elastic modulus. The incorporation of sol-gel-derived BAGs, especially BAG87, into dentin adhesives enhances the remineralization and mechanical properties of adhesive-dentin interfaces.

摘要

为克服由于粘结界面处胶原蛋白降解导致的牙本质粘结局限性,已提出将生物活性玻璃(BAG)掺入牙本质粘结剂中,以增强再矿化并提高粘结耐久性。本研究评估了掺入牙本质粘结剂中的溶胶-凝胶法制备的BAG(BAG79、BAG87、BAG91和BAG79F)以及传统的熔融淬火BAG(BAG45),以评估它们的再矿化和机械性能。通过场发射扫描电子显微镜(FE-SEM)和透射电子显微镜对BAG的表面形态进行表征。采用Brunauer-Emmett-Teller方法测量表面积。进行X射线衍射(XRD)分析以确定BAG的晶体结构。在将每种实验性牙本质粘结剂与脱矿牙本质贴合后,使用FE-SEM进行粘结剂表面分析。在应用含BAG的牙本质粘结剂后,测量处理后牙本质的弹性模量。溶胶-凝胶法制备的BAG的表面积比传统BAG大400-600倍,其中BAG87的表面积最大。XRD分析表明,溶胶-凝胶BAG中羟基磷灰石的形成更明显且更快。含有BAG87的粘结剂的牙本质表现出最高的弹性模量。将溶胶-凝胶法制备的BAG,尤其是BAG87,掺入牙本质粘结剂中可增强粘结剂-牙本质界面的再矿化和机械性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e56/11765736/ca1e7adab3ae/jfb-16-00029-g001.jpg

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本文引用的文献

2
3
Effects of bioactive glass incorporation into glass ionomer cement on demineralized dentin.
Sci Rep. 2021 Mar 29;11(1):7016. doi: 10.1038/s41598-021-86481-y.
5
Bioactive Glass Applications in Dentistry.
Int J Mol Sci. 2019 Nov 27;20(23):5960. doi: 10.3390/ijms20235960.
6
Calcium carbonate: Adored and ignored in bioactivity assessment.
Acta Biomater. 2019 Jun;91:35-47. doi: 10.1016/j.actbio.2019.04.039. Epub 2019 Apr 18.
7
Effect of bioactive glass-containing resin composite on dentin remineralization.
J Dent. 2018 Aug;75:58-64. doi: 10.1016/j.jdent.2018.05.017. Epub 2018 May 25.
8
Dual function of proanthocyanidins as both MMP inhibitor and crosslinker in dentin biomodification: A literature review.
Dent Mater J. 2018 Mar 30;37(2):173-182. doi: 10.4012/dmj.2017-062. Epub 2017 Nov 23.
9
Effects of Composites Containing Bioactive Glasses on Demineralized Dentin.
J Dent Res. 2017 Aug;96(9):999-1005. doi: 10.1177/0022034517709464. Epub 2017 May 23.
10
Sol-gel processing of bioactive glass nanoparticles: A review.
Adv Colloid Interface Sci. 2017 Nov;249:363-373. doi: 10.1016/j.cis.2017.03.008. Epub 2017 Mar 21.

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