Zedde Marialuisa, Pascarella Rosario
Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, Italy.
Neuroradiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Viale Risorgimento 80, 42123 Reggio Emilia, Italy.
Neurol Int. 2025 Jan 17;17(1):9. doi: 10.3390/neurolint17010009.
Cerebral venous thrombosis (CVT) is a rare and potentially critical cerebrovascular disease involving intracranial dural sinuses and veins. The diagnosis is a stepwise pathway starting from clinical suspicion and employing several neuroradiological techniques, mainly Computed Tomography (CT)-based and Magnetic Resonance Imaging (MRI)-based modalities. The neuroradiological findings, both in the diagnostic phase and in the follow-up phase, may provide some results at risk for misdiagnosis. Non-thrombotic filling defects of intracranial dural sinuses are among them, and the potential sources are artefactual and or anatomical (venous septa and arachnoid granulations). The misdiagnosis of these findings as CVT is potentially linked to dangerous consequences. A potential strategy to avoid this is to increase the knowledge about technical and anatomical reasons for non-thrombotic filling defects of intracranial dural sinuses and their imaging features. The main aim of this review is to address these issues, including the variability of the intracranial venous pathways, providing the solutions for overcoming the above-cited potential misdiagnosis of non-thrombotic filling defects as CVT.
脑静脉血栓形成（CVT）是一种罕见且可能危及生命的脑血管疾病，累及颅内硬脑膜窦和静脉。诊断是一个逐步的过程，始于临床怀疑，并采用多种神经放射学技术，主要是基于计算机断层扫描（CT）和磁共振成像（MRI）的方法。在诊断阶段和随访阶段，神经放射学检查结果都可能存在误诊风险。颅内硬脑膜窦的非血栓性充盈缺损就是其中之一，其潜在原因包括伪影和/或解剖结构（静脉隔和蛛网膜颗粒）。将这些表现误诊为CVT可能会导致危险后果。避免这种情况的一个潜在策略是增加对颅内硬脑膜窦非血栓性充盈缺损的技术和解剖学原因及其影像学特征的认识。本综述的主要目的是探讨这些问题，包括颅内静脉通路的变异性，为克服上述将非血栓性充盈缺损误诊为CVT的潜在问题提供解决方案。
