Aguinaga-Ontoso Ines, Guillen-Aguinaga Sara, Guillen-Aguinaga Laura, Alas-Brun Rosa, Guillen-Aguinaga Miriam, Onambele Luc, Aguinaga-Ontoso Enrique, Rayón-Valpuesta Esperanza, Guillen-Grima Francisco
Department of Health Sciences, Public University of Navarra, 31008 Pamplona, Spain.
Healthcare Research Institute of Navarra (IdiSNA), 31008 Pamplona, Spain.
Vaccines (Basel). 2024 Dec 24;13(1):6. doi: 10.3390/vaccines13010006.
The COVID-19 pandemic disrupted routine child immunization efforts, threatening to reverse progress in controlling vaccine-preventable diseases.
We analyzed the impact of COVID-19 on DTP3 vaccination in Europe by comparing trends before and after the pandemic using time series data from 2000 to 2023. Employing joinpoint regression, chi-square tests, and segmented regression analysis, we assessed DTP3 vaccination trends and coverage changes.
The findings revealed significant regional disparities across Europe. Statistical models indicated reductions in DTP3 coverage in countries such as Ireland, Sweden, and Switzerland, whereas Ukraine and San Marino showed improvements.
There are variations in the effect of COVID-19 on DTP3 coverage rates, indicating the need for targeted public health strategies to address vaccine hesitancy, logistical barriers, and systemic inequities.
新冠疫情扰乱了常规儿童免疫接种工作，有可能使在控制疫苗可预防疾病方面取得的进展倒退。
我们通过比较2000年至2023年的时间序列数据，分析了新冠疫情对欧洲百白破三联疫苗第三剂（DTP3）接种的影响。我们采用连接点回归、卡方检验和分段回归分析，评估了DTP3接种趋势和覆盖率变化。
研究结果显示欧洲各地存在显著的地区差异。统计模型表明，爱尔兰、瑞典和瑞士等国的DTP3覆盖率有所下降，而乌克兰和圣马力诺则有所提高。
新冠疫情对DTP3覆盖率的影响存在差异，这表明需要制定有针对性的公共卫生策略，以解决疫苗犹豫、后勤障碍和系统性不平等问题。
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