Lange C, Aschauer J, Hufnagel H, Pauleikhoff L
Department of Ophthalmology, St. Franziskus Hospital, Münster, Deutschland.
Eye Center, Freiburg Medical Center, University of Freiburg, 79106, Freiburg, Deutschland.
Ophthalmologie. 2025 Mar;122(3):178-185. doi: 10.1007/s00347-024-02171-w. Epub 2025 Jan 24.
The accurate diagnosis of central serous chorioretinopathy (CSC) and its distinction from differential diagnoses is crucial for effective patient counseling and treatment. This is achieved through a targeted patient history and multimodal imaging, which distinguish CSC from other ocular diseases also characterized by subretinal fluid and changes in the retinal pigment epithelium. In this article we identify the key differential diagnoses of CSC and illustrate the characteristic differential diagnostic features of each disease. The differential diagnoses of CSC can be categorized into eight groups: 1) (neo)vascular choroidal diseases, 2) retinal diseases, 3) inflammatory diseases of the posterior segment, 4) benign and malignant ocular tumors, 5) malignant hematological diseases, 6) genetic disorders, 7) ocular developmental anomalies and 8) medication-related and toxic retinal changes.
准确诊断中心性浆液性脉络膜视网膜病变(CSC)并将其与鉴别诊断区分开来,对于有效的患者咨询和治疗至关重要。这通过有针对性的患者病史和多模式成像来实现,这些方法可将CSC与其他同样以视网膜下液和视网膜色素上皮改变为特征的眼部疾病区分开来。在本文中,我们确定了CSC的关键鉴别诊断,并阐述了每种疾病的特征性鉴别诊断特征。CSC的鉴别诊断可分为八组:1)(新)血管性脉络膜疾病,2)视网膜疾病,3)后段炎症性疾病,4)良性和恶性眼肿瘤,5)恶性血液系统疾病,6)遗传性疾病,7)眼部发育异常,8)药物相关和中毒性视网膜改变。