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股骨头坏死会增加全髋关节置换术后的早期并发症发生率吗?一项日本全国性医疗索赔数据库研究。

Does Osteonecrosis of the Femoral Head Increase Early Complication Rates After Total Hip Arthroplasty? A Japanese Nationwide Medical Claims Database Study.

作者信息

Tanaka Hidetatsu, Tarasawa Kunio, Mori Yu, Kuriyama Yasuaki, Kawamata Hiroki, Fushimi Kiyohide, Fujimori Kenji, Aizawa Toshimi

机构信息

Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Department of Health Administration and Policy, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

出版信息

J Arthroplasty. 2025 Aug;40(8):2053-2059. doi: 10.1016/j.arth.2025.01.029. Epub 2025 Jan 22.

DOI:10.1016/j.arth.2025.01.029
PMID:39855403
Abstract

BACKGROUND

Osteonecrosis of the femoral head (ONFH) and osteoarthritis (OA) are two common diagnoses for patients undergoing total hip arthroplasty (THA). The early surgical complications in THA for ONFH compared to OA are inconsistently reported. Therefore, this study aimed to evaluate whether THA for ONFH was associated with early postoperative complications in comparison to THA for OA using a large database of Japanese patients.

METHODS

In this cohort study, using a Japanese national medical claims database on ONFH and OA patients undergoing THA from December 2011 to March 2023, we assessed the surgical-related complications, medical complications, and mortality during hospitalization after propensity score matching by age, sex, body mass index, and comorbidities. A total of 24,326 pairs of THAs for ONFH and OA were included.

RESULTS

In the THA for ONFH group, the odds ratios for various complications were as follows: dislocation (1.3, 95% CI [confidence interval]: 1.1 to 1.6, P < 0.01), infection (1.0, 95% CI: 0.8 to 1.2, P = 0.94), periprosthetic fracture (1.0, 95% CI: 0.8 to 1.4, P = 0.86), nerve palsy during hospitalization (0.4, 95% CI: 0.2 to 0.9, P = 0.034), pneumonia (1.7, 95% CI: 1.1 to 2.5, P < 0.01), deep vein thrombosis (0.9, 95% CI: 0.8 to 1.0, P = 0.018), pulmonary embolism (1.5, 95% CI: 0.9 to 2.5, P = 0.14), cardiac events (0.7, 95% CI: 0.3 to 2.1, P = 0.55), cerebrovascular events (0.7, 95% CI: 0.5 to 1.0, P = 0.084), acute renal failure (1.4, 95% CI: 0.4 to 4.4, P = 0.56), and mortality during hospitalization (1.8, 95% CI: 1.3 to 2.4, P < 0.01).

CONCLUSIONS

These findings contribute to identifying postoperative risks for ONFH patients and suggest that more attention should be paid to preoperative planning and postoperative care for ONFH patients.

摘要

背景

股骨头坏死(ONFH)和骨关节炎(OA)是接受全髋关节置换术(THA)患者的两种常见诊断。与OA相比,ONFH患者行THA的早期手术并发症报道不一。因此,本研究旨在利用一个大型日本患者数据库,评估与OA患者行THA相比,ONFH患者行THA是否与术后早期并发症相关。

方法

在这项队列研究中,我们使用了一个关于2011年12月至2023年3月期间接受THA的ONFH和OA患者的日本全国医疗索赔数据库,通过年龄、性别、体重指数和合并症进行倾向评分匹配后,评估住院期间的手术相关并发症、医疗并发症和死亡率。共纳入24326对ONFH和OA患者的THA病例。

结果

在ONFH患者行THA组中,各种并发症的比值比(OR)如下:脱位(1.3,95%置信区间[CI]:1.1至1.6,P<0.01)、感染(1.0,95%CI:0.8至1.2,P = 0.94)、假体周围骨折(1.0,95%CI:0.8至1.4,P = 0.86)、住院期间神经麻痹(0.4,95%CI:0.2至0.9,P = 0.034)、肺炎(1.7,95%CI:1.1至2.5,P<0.01)、深静脉血栓形成(0.9,95%CI:0.8至1.0,P = 0.018)、肺栓塞(1.5,95%CI:0.9至2.5,P = 0.14)、心脏事件(0.7,95%CI:0.3至2.1,P = 0.55)、脑血管事件(0.7,95%CI:0.5至1.0,P = 0.084)、急性肾衰竭(1.4,95%CI:0.4至4.4,P = 0.56)和住院期间死亡率(1.8,95%CI:1.3至2.4,P<0.01)。

结论

这些发现有助于识别ONFH患者的术后风险,并表明应更加关注ONFH患者的术前规划和术后护理。

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