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肌肉协调性改变以减轻肢体缺失者的膝关节负荷

Alterations in Muscle Coordination to Reduce Knee Joint Loading for People with Limb Loss.

作者信息

Hu Jiayu, Ding Ziyun, Bull Anthony M J

机构信息

School of Engineering, University of Birmingham, Birmingham, B15 2TT, UK.

Department of Bioengineering, Imperial College London, London, UK.

出版信息

Ann Biomed Eng. 2025 Apr;53(4):935-945. doi: 10.1007/s10439-025-03682-6. Epub 2025 Jan 24.

Abstract

PURPOSE

People with unilateral transtibial amputation experienced a higher incidence of knee osteoarthritis due to abnormal movement patterns. This study aimed to explore alternations in muscle coordination to reduce mechanical burdens in their daily activities.

METHODS

Five males with unilateral transtibial amputation were recruited. Two daily activities (level walking and standing up from a chair) were simulated using muscle-driven simulation. Two cost functions were applied: minimising the knee adduction moment and minimising both the knee adduction moment and knee flexion moment. This enabled the identification of altered muscle coordination and any possible changes in kinematic patterns.

RESULTS

For people with unilateral transtibial amputation, reducing knee adduction angles during stance was found effective in reducing knee adduction moments. To mitigate peak contact forces at the intact knee, muscle activations of vasti and gastrocnemius should be decreased, while muscle activations of soleus should be increased during activities of level walking and standing up from a chair.

CONCLUSION

Our study suggested that minimising knee adduction moments was effective in reducing joint loading during level walking while minimising both knee adduction moments and knee flexion moments was effective during standing up from a chair. Therefore, the alteration of muscle coordination should be carefully designed for different daily activities.

摘要

目的

单侧经胫骨截肢患者由于异常的运动模式,膝关节骨关节炎的发病率较高。本研究旨在探索肌肉协调性的改变,以减轻其日常活动中的机械负担。

方法

招募了5名单侧经胫骨截肢的男性。使用肌肉驱动模拟来模拟两项日常活动(平地行走和从椅子上站起来)。应用了两个成本函数:最小化膝关节内收力矩以及同时最小化膝关节内收力矩和膝关节屈曲力矩。这有助于识别改变的肌肉协调性以及运动学模式的任何可能变化。

结果

对于单侧经胫骨截肢患者,发现在站立期减少膝关节内收角度可有效降低膝关节内收力矩。为减轻健全膝关节处的峰值接触力,在平地行走和从椅子上站起来的活动中,应减少股四头肌和腓肠肌的肌肉激活,同时增加比目鱼肌的肌肉激活。

结论

我们的研究表明,最小化膝关节内收力矩在平地行走期间有效减少关节负荷,而同时最小化膝关节内收力矩和膝关节屈曲力矩在从椅子上站起来时有效。因此,应针对不同的日常活动仔细设计肌肉协调性的改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f50/11929717/5d8cad1d4609/10439_2025_3682_Fig1_HTML.jpg

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