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[基于三维颅面特征的正颌患者相似性测量模型的建立与评价]

[Establishment and evaluation of a similarity measurement model for orthognathic patients based on the 3D craniofacial features].

作者信息

Wu Ling, Fang Jiakun, Liu Xiaojing, Li Zili, Li Yang, Wang Xiaoxia

机构信息

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2025 Feb 18;57(1):128-135. doi: 10.19723/j.issn.1671-167X.2025.01.019.

DOI:10.19723/j.issn.1671-167X.2025.01.019
PMID:39856517
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11759787/
Abstract

OBJECTIVE

To establish a similarity measurement model for patients with dentofacial deformity based on 3D craniofacial features and to validate the similarity results with quantifying subjective expert scoring.

METHODS

In the study, 52 cases of patients with skeletal Class Ⅲ malocclusions who underwent bimaxillary surgery and preoperative orthodontic treatment at Peking University School and Hospital of Stomatology from January 2020 to December 2022, including 26 males and 26 females, were selected and divided into 2 groups by sex. One patient in each group was randomly selected as a reference sample, and the others were set as test samples. Three senior surgeons rated the similarity scores between the test samples and the reference sample. Similarity scores ranged from 1 to 10, where 1 was completely different, and 10 was exactly the same. Scores larger than 7.5 was considered as clinically similar. Preoperative cone beam computed tomography (CBCT) and 3D facial images of the patients were collected. The three-dimensional hard and soft tissue features, including distances, angles and 3D point cloud features were extracted. The similarity measurement model was then established to fit with the experts' similarity scoring by feature selection algorithm and linear regression model. To verify the reliability of the model, 14 new patients were selected and input to similarity measurement model for finding similar cases. The similarity scoring of these similar cases were rated by experts, and used to evaluate the reliability of the model.

RESULTS

The similarity metric models indicated that the features of the middle and lower craniofacial features were the main features to influence the craniofacial similarity. The main features that were related to the expert' s similarity scoring included distance of anterior nasal spine-menton (ANS-Me), distance of right upper canion point-Frankfurt horizontal plane (U3RH), distance of left superior point of the condyle-left gonion (CoL-GoL), distance of left gonion-menton (CoL-Me), distance of pogonion-midsagittal plane (Pog-MSP), distance of right alar base-left alar base (AlR-AlL), angle of pronasale-soft tissue pogonion-labrale inferius (Pn-Pog' -Li), distance of trichion-right tragus (Tri-TraR), distance of left exocanthion-left alar base (ExL-AlL), lower 1/3 of skeletal face, middle and lower 2/3 of skeletal face and upper lip region of soft tissue. Fourteen new patients were chosen to evaluate the model. The similar cases selected by the model had an average experts' similarity scoring of 7.627± 0.711, which was not significantly different with 7.5.

CONCLUSION

The similarity measurement model established by this model could find the similar cases which highly matched experts' subjective similarity scoring. The study could be further used for similar cases retrieval in skeletal Ⅲ malocclusion patients.

摘要

目的

基于三维颅面特征建立牙颌面畸形患者的相似度测量模型,并通过量化主观专家评分来验证相似度结果。

方法

本研究选取2020年1月至2022年12月在北京大学口腔医学院口腔医院接受双颌手术及术前正畸治疗的52例骨性Ⅲ类错牙合患者,其中男性26例,女性26例,按性别分为2组。每组随机选取1例患者作为参考样本,其余作为测试样本。3名资深外科医生对测试样本与参考样本之间的相似度进行评分。相似度评分范围为1至10分,其中1分表示完全不同,10分表示完全相同。得分大于7.5分被认为在临床上相似。收集患者术前锥形束计算机断层扫描(CBCT)和三维面部图像。提取三维硬组织和软组织特征,包括距离、角度和三维点云特征。然后通过特征选择算法和线性回归模型建立相似度测量模型,使其与专家的相似度评分相拟合。为验证模型的可靠性,选取14例新患者输入相似度测量模型以寻找相似病例。由专家对这些相似病例的相似度评分进行评定,并用于评估模型的可靠性。

结果

相似度度量模型表明,颅面中下部特征是影响颅面相似度的主要特征。与专家相似度评分相关的主要特征包括前鼻棘-颏点距离(ANS-Me)、右上尖牙点-法兰克福水平面距离(U3RH)、左侧髁突上点-左侧下颌角距离(CoL-GoL)、左侧下颌角-颏点距离(CoL-Me)、颏前点-正中矢状面距离(Pog-MSP)、右侧鼻翼基底-左侧鼻翼基底距离(AlR-AlL)、鼻前点-软组织颏点-下唇唇红缘角(Pn-Pog'-Li)、发际点-右侧耳屏距离(Tri-TraR)、左侧外眦点-左侧鼻翼基底距离(ExL-AlL)、骨骼面部下1/3、骨骼面部中下部2/3以及软组织上唇区域。选取14例新患者对模型进行评估。模型选取的相似病例专家相似度评分平均为7.627±0.711,与7.5分无显著差异。

结论

本研究建立的相似度测量模型能够找到与专家主观相似度评分高度匹配的相似病例。该研究可进一步用于骨性Ⅲ类错牙合患者相似病例的检索。

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Patient-specific reference model estimation for orthognathic surgical planning.基于患者特定参考模型的正颌手术规划估计。
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