Chang Jia-Ying, Chen Yen-Chang, Ding Dah-Ching
Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien 970, Taiwan.
Division of Digital Pathology, Department of Anatomical Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.
Diagnostics (Basel). 2025 Jan 14;15(2):173. doi: 10.3390/diagnostics15020173.
Spiradenoma is a rare benign skin adnexal tumor with unknown incidence and prevalence, typically affecting young to middle-aged adults without a sexual predilection. A 59-year-old woman presented with a palpable lesion in the suprapubic region that had been there for 20 years and had become enlarged over the past 2 months. Physical examination revealed a firm, non-tender, subcutaneous mass, approximately 2 cm in size, in the right pubic region. Ultrasound revealed a hypoechoic, heterogeneous lesion with a well-defined border, measuring 2.37 × 0.94 × 1.67 cm, without hypervascularity. Therefore, the patient underwent excision of the subcutaneous tumor. The pathology report confirmed the diagnosis of spiradenoma of the pubis. Histochemistry showed that the inner luminal cells were positive for CK7, and the outer basaloid cells were positive for p63. CD56 and CD117 were focally positive. With an accurate diagnosis and appropriate surgical excision, the prognosis for spiradenoma is generally excellent. However, a long-term follow-up is advisable.
汗腺螺旋瘤是一种罕见的良性皮肤附属器肿瘤，发病率和患病率未知，通常影响中青年，无性别倾向。一名59岁女性，耻骨上区域出现可触及的肿物20年，在过去2个月内增大。体格检查发现右耻骨区域有一个质地坚硬、无压痛的皮下肿物，大小约2 cm。超声显示一个边界清晰的低回声、不均匀肿物，大小为2.37×0.94×1.67 cm，无血管增多。因此，患者接受了皮下肿瘤切除术。病理报告证实为耻骨汗腺螺旋瘤。免疫组化显示，管腔内细胞CK7阳性，外层基底样细胞p63阳性。CD56和CD117局灶性阳性。通过准确诊断和适当的手术切除，汗腺螺旋瘤的预后通常良好。然而，建议进行长期随访。
