Alshehri Sarah, Alasmari Thikra Khalid Hamdi
Otology and Neurotology, Department of Surgery, College of Medicine, King Khalid University, Abha 61423, Saudi Arabia.
Diagnostics (Basel). 2025 Jan 14;15(2):186. doi: 10.3390/diagnostics15020186.
This study aims to evaluate factors influencing revision cochlear implant surgeries, including patient demographics, surgical techniques, and radiological findings. The main aim was to identify factors influencing surgical success to inform clinical treatment and enhance patient outcomes. This cross-sectional study included adult patients over the age of 18 who underwent revision cochlear implant surgery due to implant-related complications. Data were collected from systematic chart reviews of electronic medical records, including demographics, surgical techniques, radiological output from standard high-resolution CT and MRI, and intraoperative data. The primary outcome was surgical success, defined by improved auditory function, stable device positioning, and absence of postoperative complications. Statistical analyses, including multivariate logistic regression, were conducted to identify independent predictors of surgical success. A total of 188 patients were included, with a mean age of 45.67 years. Younger age, shorter duration of implant use, modified surgical techniques, and absence of co-morbidities are key factors contributing to surgical success. Modified surgical techniques were associated with better outcomes (39.29% vs. 68.75%, OR: 2.78, 95% CI: 1.25-6.14, = 0.012). Radiological patterns significantly affected outcomes, with normal findings associated with higher success rates. In contrast, abnormalities such as electrode migration (OR: 2.14, 95% CI: 1.12-4.09, = 0.021) and ossification (r = -0.51, β = -0.44, adjusted R = 0.25, < 0.01) were correlated with poorer results. Smoking status, when comparing smokers to non-smokers, was associated with unfavorable outcomes (20.00% vs. 45.83%, OR: 2.01, 95% CI: 1.01-4.01, = 0.048), and a history of previous surgeries (21.43% vs. 37.50%, OR: 1.95, 95% CI: 1.03-3.71, = 0.033) was significantly associated with unfavorable outcomes. Statistically, significantly better outcomes are positively correlated with the duration of the first cochlear implant experience and negatively with prior otologic pathology and nonauditory environmental influences on surgical success. Younger age, modified surgical techniques, and normal radiological findings were related to better outcomes; complications such as electrode migration and ectopic ossification were strong predictive factors for surgical failure. These findings underscore the need for tailored surgical approaches and early intervention to enhance outcomes in revision cochlear implant surgeries.
本研究旨在评估影响人工耳蜗翻修手术的因素,包括患者人口统计学特征、手术技术和影像学检查结果。主要目的是确定影响手术成功的因素,为临床治疗提供依据并改善患者预后。这项横断面研究纳入了18岁以上因植入相关并发症而接受人工耳蜗翻修手术的成年患者。数据通过对电子病历的系统图表回顾收集,包括人口统计学信息、手术技术、标准高分辨率CT和MRI的影像学检查结果以及术中数据。主要结局指标为手术成功,定义为听觉功能改善、装置位置稳定且无术后并发症。进行了包括多因素逻辑回归在内的统计分析,以确定手术成功的独立预测因素。共纳入188例患者,平均年龄为45.67岁。年龄较小、植入使用时间较短、改良手术技术以及无合并症是手术成功的关键因素。改良手术技术与更好的结局相关(39.29%对68.75%,OR:2.78,95%CI:1.25 - 6.14,P = 0.012)。影像学表现显著影响结局,正常表现与较高的成功率相关。相比之下,电极移位(OR:2.14,95%CI:1.12 - 4.09,P = 0.021)和骨化(r = -0.51,β = -0.44,调整后R = 0.25,P < 0.01)等异常情况与较差的结果相关。比较吸烟者与非吸烟者时,吸烟状态与不良结局相关(20.00%对45.83%,OR:2.01,95%CI:1.01 - 4.01,P = 0.048),既往手术史(21.43%对37.50%,OR:1.95,95%CI:1.03 - 3.71,P = 0.033)也与不良结局显著相关。从统计学角度来看,明显更好的结局与首次人工耳蜗植入经历的时长呈正相关,而与既往耳科病理情况以及手术成功的非听觉环境影响呈负相关。年龄较小、改良手术技术和正常影像学表现与更好的结局相关;电极移位和异位骨化等并发症是手术失败的强烈预测因素。这些发现强调了需要采用个性化的手术方法和早期干预措施,以改善人工耳蜗翻修手术的结局。