Calderone Andrea, Marra Angela, De Luca Rosaria, Latella Desirèe, Corallo Francesco, Quartarone Angelo, Tomaiuolo Francesco, Calabrò Rocco Salvatore
Department of Clinical and Experimental Medicine, University of Messina, Piazza Pugliatti, 98122 Messina, Italy.
IRCCS Centro Neurolesi Bonino-Pulejo, S.S. 113 Via Palermo, C.da Casazza, 98124 Messina, Italy.
Biomedicines. 2025 Jan 9;13(1):149. doi: 10.3390/biomedicines13010149.
: Dementia leads to cognitive decline, affecting memory, reasoning, and daily activities, often requiring full-time care. Multisensory stimulation (MSS), combined with cognitive tasks, can slow this decline, improving mood, communication, and overall quality of life. This systematic review aims to explore methods that utilize MSS in the rehabilitation of patients with dementia. Its clinical value is rooted in its ability to offer a deep comprehension of how MSS can be successfully incorporated into rehabilitation treatments. : Studies were identified from an online search of PubMed, EBSCOhost, Cochrane Library, Web of Science, Embase, and Scopus databases with a search time frame from 2014 to 2024. This review has been registered on Open OSF (n) 3KUQX. : Pilot studies investigating MSS interventions, encompassing Cognitive Stimulation Therapy (CST), Sonas therapy, and combined physical-cognitive exercise programs, have yielded mixed findings in individuals with dementia. CST has demonstrated significant improvements in general cognitive function, particularly in language skills, offering a promising approach for cognitive enhancement. Sonas therapy, while showing positive trends in some studies, does not consistently achieve statistically significant outcomes across all cognitive domains. Conversely, combined exercise programs have shown efficacy in improving dual-task performance, suggesting benefits for motor-cognitive integration. MSS delivered within specialized environments like Snoezelen rooms consistently produces positive effects on mood, reducing agitation and promoting relaxation. : This review emphasizes how MSS can enhance cognitive, emotional, and behavioral results for individuals with dementia. It is essential for future research to standardize protocols, incorporate advanced technologies such as virtual reality, and rectify diversity gaps. Collaboration between different fields will improve the effectiveness and usefulness of MSS in caring for individuals with dementia.
痴呆症会导致认知能力下降，影响记忆、推理和日常活动，通常需要全职护理。多感官刺激（MSS）与认知任务相结合，可以减缓这种下降，改善情绪、沟通和整体生活质量。本系统评价旨在探索在痴呆症患者康复中利用MSS的方法。其临床价值在于能够深入理解如何将MSS成功纳入康复治疗。
通过对PubMed、EBSCOhost、Cochrane图书馆、Web of Science、Embase和Scopus数据库进行在线搜索，确定了2014年至2024年期间的研究。本评价已在Open OSF（n）3KUQX上注册。
对包括认知刺激疗法（CST）、索纳斯疗法和身体-认知联合锻炼计划在内的MSS干预进行的初步研究，在痴呆症患者中得出了不同的结果。CST已证明在一般认知功能方面有显著改善，尤其是在语言技能方面，为认知增强提供了一种有前景的方法。索纳斯疗法虽然在一些研究中显示出积极趋势，但在所有认知领域并非都能始终取得统计学上的显著结果。相反，联合锻炼计划已显示出在改善双任务表现方面的效果，表明对运动-认知整合有益。在如多感官环境房等特殊环境中提供的MSS始终对情绪产生积极影响，减少躁动并促进放松。
本评价强调了MSS如何能增强痴呆症患者的认知、情感和行为效果。未来研究必须规范方案，纳入虚拟现实等先进技术，并纠正多样性差距。不同领域之间的合作将提高MSS在照顾痴呆症患者方面的有效性和实用性。
