Faculty of Music, St. George Campus, University of Toronto, 80 Queens Park, Toronto, ON M5S 2C5, Canada.
Int J Environ Res Public Health. 2022 Nov 23;19(23):15553. doi: 10.3390/ijerph192315553.
Dementia prevalence is increasing globally, and symptom management and treatment strategies require further investigation. Music-based interventions have demonstrated some efficacy with respect to quality of life and symptom reduction, though limited with respect to cognition. This study reports on three case studies where the use of gamma stimulation over one year contributed to maintenance of cognition and increases in mood for participants with Alzheimer's disease or mild cognitive impairment. Auditory stimulation with isochronous sound at 40 Hz was delivered to participants via a commercially available vibroacoustic chair device five times per week for 30 min with assistance from caregivers. Further research is needed to assess the integration of this therapy in the overall care for persons with dementia.
痴呆症的患病率在全球范围内不断上升，因此需要进一步研究症状管理和治疗策略。基于音乐的干预措施已被证明在改善生活质量和减轻症状方面具有一定的效果，但对认知的影响有限。本研究报告了三个案例研究，其中使用伽马刺激一年以上有助于维持认知功能，并改善阿尔茨海默病或轻度认知障碍患者的情绪。通过商业上可获得的振动声椅设备，每周五次向参与者提供 40 Hz 的等时声音听觉刺激，每次 30 分钟，由护理人员协助。需要进一步的研究来评估这种疗法在痴呆症患者整体护理中的整合。
