Ferrell Brandon E, Thomas Jason, Skendelas John P, Uehara Mayuko, Sugiura Tadahisa
Montefiore Medical Center, Department of Cardiothoracic and Vascular Surgery, Bronx, NY 10467, USA.
Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Biomedicines. 2025 Jan 15;13(1):204. doi: 10.3390/biomedicines13010204.
Extracorporeal cardiopulmonary resuscitation (eCPR) is a method of acute resuscitation for patients who have suffered a cardiac arrest through the utilization of an extracorporeal membrane oxygenation (ECMO) pump. The use and efficacy of eCPR is an active area of investigation with ongoing clinical investigation across the world. Since its inception, ECMO has been utilized for several conditions, but more recently, its efficacy in maintaining cerebrovascular perfusion in eCPR has generated interest in more widespread utilization, particularly in cases of out-of-hospital cardiac arrest. However, successful implementation of eCPR can be technically challenging and resource intensive and has been countered with ethical challenges beyond the scope of conventional in-hospital ECMO care. The aim of this review is to summarize the status of eCPR in the current era.
体外心肺复苏(eCPR)是一种通过使用体外膜肺氧合(ECMO)泵对心脏骤停患者进行急性复苏的方法。eCPR的使用和疗效是一个活跃的研究领域,全球正在进行临床研究。自问世以来,ECMO已被用于多种病症,但最近,其在eCPR中维持脑血管灌注的疗效引发了人们对更广泛应用的兴趣,特别是在院外心脏骤停的情况下。然而,成功实施eCPR在技术上具有挑战性且资源密集,并且还面临着传统院内ECMO护理范围之外的伦理挑战。本综述的目的是总结当前时代eCPR的现状。