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产后晚期子痫伴后部可逆性脑病综合征及蛛网膜下腔出血:病例报告

Late Postpartum Eclampsia with Posterior Reversible Encephalopathy Syndrome and Subarachnoid Hemorrhage: A Case Study.

作者信息

Elshafei Mohamed, Oweis Hala Ashraf, Abdul Hafez Yosra, Alom Thuraya, Hayani Zahraa Mohamed, ElNebrisi Eslam

机构信息

Department of Neurology, Zulekha Hospital, Dubai 48577, United Arab Emirates.

Department of Internal Medicine, Dubai Medical College for Girls, Dubai 20170, United Arab Emirates.

出版信息

Medicina (Kaunas). 2025 Jan 5;61(1):77. doi: 10.3390/medicina61010077.

Abstract

Eclampsia is a multisystem disorder of pregnancy and the puerperium. Posterior reversible encephalopathy syndrome (PRES), a neurotoxic condition characterized by various neurological symptoms, can arise from multiple causes including eclampsia. Although hemorrhage is a possible complication of PRES, subarachnoid hemorrhage (SAH) is a rare occurrence in eclamptic patients with this condition. A 33-year-old female patient presented with acute severe headache and blurred vision two days after delivery. This progressively worsened over the next five days before she was admitted to the hospital. A magnetic resonance imaging (MRI) brain scan with contrast revealed a picture suggestive of PRES. Following admission, she had seizures, and a follow-up MRI revealed an acute subarachnoid hemorrhage. Treatment started, and the patient improved and was discharged from the hospital without any residual symptoms. This case illustrates how eclampsia can be a risk factor for PRES, and although hemorrhagic PRES is becoming more recognized, SAH remains an unusual but critical presentation. Early and accurate diagnosis, along with effective management, is crucial for achieving a positive outcome.

摘要

子痫是一种妊娠和产褥期的多系统疾病。后部可逆性脑病综合征(PRES)是一种以各种神经症状为特征的神经毒性疾病,可由多种原因引起,包括子痫。虽然出血是PRES的一种可能并发症,但蛛网膜下腔出血(SAH)在患有这种疾病的子痫患者中很少见。一名33岁女性患者在分娩两天后出现急性严重头痛和视力模糊。在入院前的接下来五天里,病情逐渐恶化。增强磁共振成像(MRI)脑部扫描显示出提示PRES的图像。入院后,她发生了癫痫发作,后续MRI显示有急性蛛网膜下腔出血。治疗开始后,患者病情好转并出院,没有任何残留症状。该病例说明了子痫如何成为PRES的一个危险因素,虽然出血性PRES越来越受到认可,但SAH仍然是一种不常见但严重的表现。早期准确诊断以及有效管理对于取得良好结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82b/11767126/6cb91f25d399/medicina-61-00077-g001.jpg

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