Barth Iris, Stevens Corien L, Peters Vera, Lucassen Desiree A, Feskens Edith J M, Dijkstra Gerard, Campmans-Kuijpers Marjo J E
Department of Gastroenterology and Hepatology, University Medical Centre Groningen (UMCG), 9713 GZ Groningen, The Netherlands.
Graduate School of Medical Sciences (GSMS), University of Groningen (RUG), 9700 AB Groningen, The Netherlands.
Nutrients. 2025 Jan 10;17(2):239. doi: 10.3390/nu17020239.
To assess nutritional intake of patients with inflammatory bowel disease (IBD), a disease-specific food frequency questionnaire (FFQ) was developed: the Groningen IBD Nutritional Questionnaire (GINQ-FFQ). Aim of this study was to assess the relative validity of the GINQ-FFQ. Between 2019 and 2022, participants of the 1000IBD cohort were included and filled out a 3-day food diary and the GINQ-FFQ. Nutritional intake of nutrients and food groups was calculated. Bland-Altman analysis was conducted for energy intake, while paired -tests and Wilcoxon signed rank tests were used for nutrient and food group intake. Additionally, group-level bias, cross-classification, and correlation analysis were performed. 142 patients (59.2% females, mean age of 49 ± 14 years) were included. Bland-Altman analysis showed a mean difference between the GINQ-FFQ and 3FD of -63.6 kcal (±638.4), with limits of agreement ranging from -1315 to 1188 kcal. Differences in energy intake was significantly associated with higher mean total energy intake ( < 0.001). When stratifying for sex, this association only was significant for males. Group-level bias showed that the GINQ-FFQ tends to result in lower intake reports for macro- and micronutrients. Ranking ability (cross-classification) of macro-, micronutrients and food groups was good. Correlation coefficients for nutrients and food groups were considered acceptable or good. Overall, the GINQ-FFQ is a valid food frequency questionnaire to assess nutritional intake specifically for patients with IBD. However, for males with high total energy intakes, dietary assessment could be less accurate.
为评估炎症性肠病（IBD）患者的营养摄入情况，研发了一种疾病特异性食物频率问卷（FFQ）：格罗宁根IBD营养问卷（GINQ-FFQ）。本研究的目的是评估GINQ-FFQ的相对效度。在2019年至2022年期间，纳入了1000IBD队列的参与者，他们填写了一份3天的食物日记和GINQ-FFQ。计算了营养素和食物组的营养摄入量。对能量摄入进行了布兰德-奥特曼分析，而对营养素和食物组的摄入量则使用了配对t检验和威尔科克森符号秩检验。此外，还进行了组水平偏差、交叉分类和相关性分析。共纳入142例患者（女性占59.2%，平均年龄49±14岁）。布兰德-奥特曼分析显示，GINQ-FFQ与3天食物日记之间的平均差异为-63.6千卡（±638.4），一致性界限为-1315至1188千卡。能量摄入差异与较高的平均总能量摄入显著相关（P<0.001）。按性别分层时，这种关联仅在男性中显著。组水平偏差表明，GINQ-FFQ往往会导致对宏量和微量营养素的摄入量报告较低。宏量营养素、微量营养素和食物组的排序能力（交叉分类）良好。营养素和食物组的相关系数被认为是可接受的或良好的。总体而言，GINQ-FFQ是一种有效的食物频率问卷，可专门用于评估IBD患者的营养摄入情况。然而，对于总能量摄入较高的男性，饮食评估可能不太准确。
