Eichenauer Elisabeth, Sykora Christina, Ortmayr Karin, Glasl Sabine
Department of Pharmaceutical Sciences, Division of Pharmacognosy, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.
Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria.
Plants (Basel). 2025 Jan 18;14(2):266. doi: 10.3390/plants14020266.
The aerial parts (Herba Saniculae) and the underground parts (Radix Saniculae) of (sanicle) have been used traditionally in Austrian folk medicine to treat wounds. Interestingly, in the Austrian vernacular, "Radix Saniculae" can also refer to the underground parts of . This ambiguity can lead to mistakes in using these two plants and, importantly, adulterations. The present work aims to shed light on using Radix Saniculae as a wound-healing agent. Thus, the main components in the aerial and the scarcely investigated underground parts of were identified and compared to the underground parts of . For this purpose, different analytical techniques were employed: TLC, HPLC-DAD/ELSD, UHPLC-ESI-MS, and GC-MS. The main components in both and plant extracts were saccharides. Both parts of showed similar compositions: hydroxycinnamic acid derivatives and triterpene saponins. In contrast, the underground parts of contain two glucosinolates and their breakdown products. These findings suggest the same wound-healing activity for the underground parts of as was already found for its aerial parts. The glucosinolates detected in substantiate its use in wound healing. Nevertheless, the presented analytical methods allow for easy discovery of adulterations.
黑儿波的地上部分（黑儿波草）和地下部分（黑儿波根）在奥地利民间医学中传统上用于治疗伤口。有趣的是，在奥地利方言中，“黑儿波根”也可指黑儿波的地下部分。这种歧义可能导致在使用这两种植物时出现错误，重要的是，会导致掺假。本研究旨在阐明黑儿波根作为伤口愈合剂的用途。因此，对黑儿波地上部分和鲜少研究的地下部分中的主要成分进行了鉴定，并与黑儿波的地下部分进行了比较。为此，采用了不同的分析技术：薄层色谱法（TLC）、高效液相色谱 - 二极管阵列检测/蒸发光散射检测器法（HPLC - DAD/ELSD）、超高效液相色谱 - 电喷雾质谱法（UHPLC - ESI - MS）和气相色谱 - 质谱法（GC - MS）。黑儿波地上部分和地下部分植物提取物中的主要成分均为糖类。黑儿波的地上部分和地下部分显示出相似的成分：羟基肉桂酸衍生物和三萜皂苷。相比之下，黑儿波的地下部分含有两种硫代葡萄糖苷及其分解产物。这些发现表明，黑儿波的地下部分具有与地上部分相同的伤口愈合活性。在黑儿波中检测到的硫代葡萄糖苷证实了其在伤口愈合中的用途。然而，所介绍的分析方法有助于轻松发现掺假情况。
