巴西城市地区接触正痘病毒的家犬。

Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil.

作者信息

de Meneses Débora, Stoffella-Dutra Ana G, Blaso Vicenzo S, de Almeida Iara M, Dias Karolina L, Domingos Iago José da S, Ribeiro Gabriela P, Coura-Vital Wendel, Reis Alexandre B, Vieira Thallyta M, Trindade Giliane de S

机构信息

Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos, 6627, Belo Horizonte 31270-901, Brazil.

Departamento de Análises Clínicas, Escola de Farmácia, Campus Morro do Cruzeiro, Universidade Federal de Ouro Preto, Morro do Cruzeiro, s/n, Ouro Preto 35402-163, Brazil.

出版信息

Viruses. 2025 Jan 17;17(1):131. doi: 10.3390/v17010131.

DOI:10.3390/v17010131

PMID:39861920

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11768714/

Abstract

Domestic animals can share viral pathogens with humans, acting mainly as a bridge host. The genus hosts important zoonotic species that have emerged in urban areas worldwide. Nevertheless, the role of companion animals, such as dogs and cats, in the circulation of orthopoxviruses in urban areas remains poorly understood. Therefore, the objective of this study was to evaluate the presence of neutralizing anti-orthopoxvirus antibodies in serum samples from owned dogs from three municipalities in Minas Gerais, as well as the presence of the C11R and A56R orthopoxviruses genes. The presence of neutralizing antibodies was detected in 14.3% of the animals investigated. However, no sample was positive for the presence of the genes investigated. Further study of the population of dogs in urban areas may prove a valuable tool for understanding the spread of orthopoxviruses in urbanized areas of Brazil.

摘要

家畜可与人类共享病毒病原体，主要充当桥梁宿主。该属宿主包含在全球城市地区出现的重要人畜共患病物种。然而，伴侣动物，如狗和猫，在城市地区正痘病毒传播中的作用仍知之甚少。因此，本研究的目的是评估来自米纳斯吉拉斯州三个城市的家养犬血清样本中抗正痘病毒中和抗体的存在情况，以及C11R和A56R正痘病毒基因的存在情况。在所调查的动物中，14.3%检测到中和抗体的存在。然而，所调查基因的样本均未呈阳性。进一步研究城市地区的犬类种群可能是了解正痘病毒在巴西城市化地区传播的宝贵工具。