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[Theory of the toroidal compact form of DNA in a polymer solution].

作者信息

Grosberg A Iu, Zhestkov A V

出版信息

Biofizika. 1985 Mar-Apr;30(2):233-8.

PMID:3986225
Abstract

A diagram of the states of single long rigid DNA macromolecule in solution of short flexible polymer was plotted. It has been shown that the compacting effect of the polymer solvent on DNA can be interpreted as hydrostatic pressure of coils gas on impermeable "walls" of the DNA globule. Conditions were found for the existence of compact (globular) states in the form of a sphere (stable for a very long DNA) and tore (for a relatively short one). Possibility of intramolecular liquidcrystalline orderliness of DNA segments in a globule was analyzed. Regions of realization of both regimes were studied: when compression with an added polymer was equalized by the forces of steric repulsion of DNA segments and when it was balanced by the elasticity of the DNA chain bendings.

摘要

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