Elger Tania, Prodan Natalia, Bettecken Kristina, Sonek Jiri, Kagan Karl Oliver
Department of Obstetrics and Gynaecology, University Hospital Tübingen, University of Tübingen, Calwerstrasse 7, 72076, Tübingen, Germany.
Division of Maternal Fetal Medicine, Boonshoft School of Medicine, Wright State University, Dayton, USA.
Arch Gynecol Obstet. 2025 Jun;311(6):1705-1710. doi: 10.1007/s00404-024-07924-1. Epub 2025 Jan 25.
To examine the impact of a new image enhancement technique on the distribution of NT measurements.
In this retrospective study, nuchal translucency (NT) images that were taken with the GE Voluson E22 ultrasound machine between May and September 2024 were collected. One operator took manual and automated NT measurements in an NT image without radiant enhancement mode followed by automated measurements in NT images with minimum, medium and maximum radiant mode. The automated measurement in the NT images without radiant mode were considered gold standard. The relative bias of the gold standard, the manual measurement and the automated measurements with the radiant enhancement technology were compared using median and 25-75th interquartile range as well as by the Wilcoxon test.
The database search yielded 352 NT images from 101 pregnant women. Average maternal age of the study population was 34.0 years and average crown-rump length was 68.3. The median NT thickness was 1.7 mm for both the manual and automated measurements done without the use of radiant mode. The median automated measurement with minimum, medium and maximum radiant mode was 2.00, 2.05 and 2.10 mm, respectively. All automated measurements were significantly higher than the gold standard.
The use of the radiant mode results in an increase in the NT thickness. This effect should be taken into account when calculating the risk for chromosomal abnormalities.
研究一种新的图像增强技术对颈部透明带(NT)测量值分布的影响。
在这项回顾性研究中,收集了2024年5月至9月期间使用GE Voluson E22超声机器采集的颈部透明带(NT)图像。一名操作人员在未开启辐射增强模式的NT图像中进行手动和自动NT测量,随后在开启最小、中等和最大辐射模式的NT图像中进行自动测量。未开启辐射模式的NT图像中的自动测量值被视为金标准。使用中位数和第25-75百分位数区间以及Wilcoxon检验比较金标准、手动测量值和采用辐射增强技术的自动测量值的相对偏差。
数据库搜索得到来自101名孕妇的352张NT图像。研究人群的平均产妇年龄为34.0岁,平均头臀长度为68.3。在未使用辐射模式进行的手动和自动测量中,NT厚度的中位数均为1.7mm。在最小、中等和最大辐射模式下自动测量的中位数分别为2.00、2.05和2.10mm。所有自动测量值均显著高于金标准。
使用辐射模式会导致NT厚度增加。在计算染色体异常风险时应考虑这种影响。