Department of Obstetrics and Gynaecology, University of Tuebingen, Germany.
Prenat Diagn. 2011 Dec;31(13):1229-33. doi: 10.1002/pd.2868. Epub 2011 Oct 24.
To compare the intraoperator and interoperator repeatability of manual and semi-automated measurement of increased nuchal translucency (NT) in sonographers with different levels of experience.
One hundred NT images without measurements were selected from the digital database. Half had NT measurements between 2.5 and 3.5 mm, and half had NT measurements above 3.5 mm. Five operators (two experts, three general gynaecologist) measured fetal NT manually and automatically. Each operator was blinded to any pre-existing measurements. Each image was measured twice by each operator. Intraoperator repeatability was assessed by standard deviation of within sonographer repeated measurement. Interoperator repeatability was assessed as difference towards the gold standard, which was defined as the mean measurement of experts.
The overall standard deviation of the difference between the first and the second manual measurements was 0.14 and 0.10 mm for moderate and severely increased NT. It was 0.10 and 0.08 mm with the semi-automated system. Mean difference between the manual measurement of nonexpert operators and the gold standard was -0.01 mm for moderately increased NT and 0.02 mm for severely increased NT. With the semi-automated measurement, mean bias was similar.
The automated NT measurement leads to a further standardization of the NT assessment process. Especially inexperienced operators may benefit from this tool.
比较不同经验水平的超声医师手动和半自动测量增厚的颈项透明层(NT)的操作者内和操作者间可重复性。
从数字数据库中选择 100 张没有测量值的 NT 图像。其中一半的 NT 值在 2.5 至 3.5mm 之间,另一半的 NT 值大于 3.5mm。5 名操作人员(2 名专家,3 名普通妇科医生)手动和自动测量胎儿 NT。每位操作员均对任何预先存在的测量值不知情。每位操作员对每张图像均进行两次测量。操作者内可重复性通过超声医师重复测量的标准差评估。操作者间可重复性评估为与金标准的差异,金标准定义为专家的平均测量值。
第一次和第二次手动测量之间差异的总体标准差分别为 0.14mm 和 0.10mm,适用于中度和重度增厚的 NT。使用半自动系统的标准差分别为 0.10mm 和 0.08mm。非专家操作员手动测量值与金标准的平均差值为中度增厚 NT 为-0.01mm,重度增厚 NT 为 0.02mm。半自动测量的平均偏差相似。
自动 NT 测量进一步实现了 NT 评估过程的标准化。特别是经验不足的操作人员可能会受益于该工具。