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生物活性玻璃(Biodentine®)和氢氧化钙在深龋病变中牙本质桥形成的评估

Evaluation of Biodentine® and Calcium Hydroxide in the Formation of Dentin Bridge in Deep Carious Lesions.

作者信息

Oburo F O, Adegbulugbe I C, Awotile A O, Enone L L, Oyapero A

机构信息

Restorative Dentistry Department, Lagos State University Teaching Hospital, Ikeja, Lagos State, Nigeria Telephone: 09070213686; Email Address:

Department of Restorative Dentistry, College of Medicine, University of Lagos/Lagos University Teaching Hospital, Idi-Araba, Lagos State, Nigeria.

出版信息

West Afr J Med. 2024 Sep 30;41(9):927-936.

PMID:39862396
Abstract

BACKGROUND

Indirect pulp capping is the main treatment modality for reversible pulpitis.

OBJECTIVE

To evaluate the efficacy of Biodentine® and Calcium hydroxide in the formation of dentin bridge.

MATERIALS AND METHODS

A double blinded, randomized clinical control trial involving 50 consenting subjects, aged 16 to 55 years with deep carious vital teeth. It was a comparative study with intervention comparing Biodentine® (test) and Calcium hydroxide (control). Subjects' teeth were assessed for normal response to pulp testing. Cavity preparation was done and the cavity was dressed with either Biodentine® or Calcium hydroxide (Ca(OH)2) then restored with Glass ionomer cement. A bitewing digital dental x-ray was taken at the end of the procedure to measure radiographically the dentin depth as base line using a digital meter. The subjects' teeth were examined radiographically at three, six and nine months. The probability level of p<0.05 was considered significant.

RESULTS

There was a progressive increase in dentin formation at three months, six months and a significant increase at nine months: the subjects' teeth in the Biodentine® group recorded an increase in dentin depth of mean 0.67±0.07mm in the mesial aspect and mean 0.66±0.07mm in both the middle and distal aspects. The Ca(OH)2 group recorded an increase in dentin depth of mean 0.55±0.07mm in the mesial aspect, mean 0.52±0.07mm in the middle aspect and mean 0.55±0.07mm in the distal aspect at nine months. (p value 0.001).

CONCLUSION

Biodentine® and Ca(OH)2 have proven to be efficacious in dentin bridge formation. The Biodentine® group showed a statistically significant increase in mean dentin depth relative to that of Ca(OH)2 group following indirect pulp capping of deeply carious teeth.

摘要

背景

间接盖髓术是治疗可复性牙髓炎的主要治疗方式。

目的

评估 Biodentine® 和氢氧化钙在牙本质桥形成中的疗效。

材料与方法

一项双盲、随机临床对照试验,纳入了 50 名年龄在 16 至 55 岁之间、有深龋活髓牙且同意参与的受试者。这是一项干预性比较研究,比较 Biodentine®(试验组)和氢氧化钙(对照组)。对受试者的牙齿进行牙髓测试以评估其正常反应。进行窝洞预备,窝洞分别用 Biodentine® 或氢氧化钙(Ca(OH)2)覆盖,然后用玻璃离子水门汀修复。在操作结束时拍摄咬合翼片数字化牙科 X 光片,使用数字测量仪在影像学上测量牙本质深度作为基线。在三个月、六个月和九个月时对受试者的牙齿进行影像学检查。p<0.05 的概率水平被认为具有统计学意义。

结果

在三个月、六个月时牙本质形成逐渐增加,在九个月时显著增加:Biodentine® 组受试者牙齿的近中面牙本质深度平均增加 0.67±0.07mm,中间面和远中面平均增加 0.66±0.07mm。在九个月时,Ca(OH)2 组近中面牙本质深度平均增加 0.55±0.07mm,中间面平均增加 0.52±0.07mm,远中面平均增加 0.55±0.07mm。(p 值 0.001)。

结论

Biodentine® 和 Ca(OH)2 已被证明在牙本质桥形成中有效。在对深龋牙齿进行间接盖髓术后,Biodentine® 组相对于 Ca(OH)2 组在平均牙本质深度上有统计学意义的显著增加。

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