[大鼠遗传性自发性高血压中肾髓质间质细胞的脂质颗粒度和形态特征]
[Lipid granularity and topographic characteristics of renomedullary interstitial cells in genetically spontaneous hypertension in rats].
作者信息
Tsibel' B N, Nefedova E V
出版信息
Biull Eksp Biol Med. 1985 Mar;99(3):358-60.
Light microscopy was used to study lipid granularity of the renomedullary interstitial cells (IC) in spontaneously hypertensive rats (SHR) aged 4 months and in Wistar rats (control) of the same age. Altogether 2000 IC were examined per animal on an average. The concentric distribution of the granular IC in the renal papilla was demonstrated. Lipid granularity of the IC was discovered to be lowered and the zone of granular IC to be enlarged in the whole papilla in SHR rats as compared with control. Also, the differences were found in lipid granularity of the IC in individual zones of the papilla in both SHR and normotensive animals, which seems likely to indicate different functional significance of the individual parts of the renal papilla.
采用光学显微镜研究4月龄自发性高血压大鼠（SHR）和同龄Wistar大鼠（对照）肾髓质间质细胞（IC）的脂质颗粒度。每只动物平均共检查2000个IC。结果显示肾乳头中颗粒状IC呈同心分布。与对照组相比，发现SHR大鼠整个肾乳头中IC的脂质颗粒度降低，颗粒状IC区域扩大。此外，在SHR大鼠和血压正常动物的肾乳头各个区域的IC脂质颗粒度上也发现了差异，这似乎表明肾乳头各个部分具有不同的功能意义。
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