Göretzlehner G
Z Gesamte Inn Med. 1979 Oct 15;34(20):624-8.
Hypertrichosis and virilisation are to be differed from hirsutism, the increased hairiness of male type in the female. The subdivision is done according to the causes into physiologic, symptomatic, iatrogenic and idiopathic forms of hirsutism and for practice adequate to localisation into degrees of severity. In pathogenesis age, race, heredity, endocrine factors of the skin, in particular the reactivity of the hair follicles, testosteron and prestages of androgen, the sexual steroid-binding globulin as well as the oestrogen-androgen-balance play a role. Despite all progress in the analytics of hormones by the catheterism of the ovarial veins and the adrenocortical veins the inhibition and stimulation tests with determination of the steroids in the plasma or in the urine are entitled to diagnostics. The treatment is performed according to the cause operatively, medicamentously or cosmetically. The best results were gained with the antiandrogens (cyproterone acetate) and the gestagen chlormadinon acetate.
多毛症和男性化应与女性男性型毛发增多的多毛症相区别。根据病因，多毛症可细分为生理性、症状性、医源性和特发性等类型，在实际应用中，还可根据严重程度进行定位分级。在发病机制方面，年龄、种族、遗传、皮肤的内分泌因素，特别是毛囊的反应性、睾酮及雄激素前体、性类固醇结合球蛋白以及雌激素与雄激素的平衡都起着作用。尽管通过卵巢静脉和肾上腺皮质静脉插管进行激素分析取得了诸多进展，但血浆或尿液中类固醇测定的抑制和刺激试验仍有助于诊断。治疗根据病因采用手术、药物或美容方法进行。使用抗雄激素药物（醋酸环丙孕酮）和孕激素醋酸氯地孕酮可取得最佳效果。
