[通过将细胞系移植到无胸腺小鼠和大鼠体内建立人肿瘤株]
[Establishment of human tumor strains from cell lines transplanted into athymic mice and rats].
作者信息
Revazova E S, Solov'ev Iu N, Khizhniakova T M, Iudicheva T V
出版信息
Biull Eksp Biol Med. 1985 Apr;99(4):469-71.
PMID:3986371
Abstract
The authors describe human cancer strains established from 6 cell lines transplanted to nude mice and rats: cancer of the liver, colon, lung, bladder and Burkitt's lymphoma. In spite of a long history (for several years) of cell line transfers in vitro, on transplantation of tumor cells, nude animals established tumors histologically identical to the primary cancer.
摘要
作者描述了从移植到裸鼠和大鼠体内的6种细胞系建立的人类癌症菌株：肝癌、结肠癌、肺癌、膀胱癌和伯基特淋巴瘤。尽管体外细胞系传代已有很长历史（数年），但肿瘤细胞移植后，裸鼠体内形成的肿瘤在组织学上与原发癌相同。
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