[可移植到无胸腺小鼠和大鼠体内的人类黑色素瘤菌株]
[Human melanoma strains transplantable into athymic mice and rats].
作者信息
Revazova E S, Solov'ev Iu N, Litvinova L V, Kochetkova O D
出版信息
Biull Eksp Biol Med. 1985 Apr;99(4):481-3.
PMID:3986377
Abstract
Malignant melanoma operative specimens from 3 patients, containing a substantial proportion of melanin as well as the MeWo cell line also containing the pigment, gave rise to human melanoma strains transplanted to nude mice and rats. All the strains demonstrated a rapid decrease in melanin production compared to the original material. The pigment was detectable by electron microscopy alone.
摘要
来自3名患者的恶性黑色素瘤手术标本，含有大量黑色素，以及同样含有色素的MeWo细胞系，产生了移植到裸鼠和大鼠体内的人黑色素瘤菌株。与原始材料相比，所有菌株的黑色素生成均迅速减少。色素仅通过电子显微镜可检测到。
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