Das Asit, Tewary Shubham, Kar Debdatta, Lakhani Gaurav, Mollah Nur Nabab, Mandal Srirupa
Department of Cardiology, Institute of Post graduate Medical Education and Research, Kolkata.
Department of Cardiology, Institute of Post graduate Medical Education and Research, Kolkata.
Am J Cardiol. 2025 May 1;242:32-36. doi: 10.1016/j.amjcard.2025.01.013. Epub 2025 Jan 24.
A total of 35 patients completed the study. Mean age was 19.8 (±4.2) years, with a male-to-female ratio of 4:3. A total of 25 patients had uncorrected TOF, and 10 had undergone intracardiac repair. After the procedure, patients with uncorrected TOF showed a significant increase in oxygen saturation from 84.7% (±1.4%) to 94.6% (±1.2%). Procedural success was 91.4%, with 3 patients experiencing significant restenosis. No procedural complications were observed. There were no arrhythmic events until the first year of follow-up. At 1-year follow-up, the mean RVOT pressure gradient was significantly decreased, and all patients remained symptom-free. In conclusion, combined balloon pulmonic valvuloplasty and conal artery occlusion is a safe and effective method for alleviating RVOT obstruction in patients with TOF, showing promising intermediate-term outcomes with minimal complications.
共有35例患者完成了该研究。平均年龄为19.8（±4.2）岁，男女比例为4:3。共有25例患者患有未经矫正的法洛四联症（TOF），10例接受了心内修复。术后，未经矫正的TOF患者的氧饱和度从84.7%（±1.4%）显著提高到94.6%（±1.2%）。手术成功率为91.4%，3例患者出现明显再狭窄。未观察到手术并发症。直到随访的第一年都没有心律失常事件发生。在1年随访时，右心室流出道（RVOT）平均压力梯度显著降低，所有患者均无症状。总之，球囊肺动脉瓣成形术联合圆锥动脉封堵术是缓解TOF患者RVOT梗阻的一种安全有效的方法，中期结果良好，并发症最少。
