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树鼩(笔尾树鼩)小脑与下丘脑之间的联系。

Connections between the cerebellum and hypothalamus in the tree shrew (Tupaia glis).

作者信息

Haines D E, Sowa T E, Dietrichs E

出版信息

Brain Res. 1985 Mar 4;328(2):367-73. doi: 10.1016/0006-8993(85)91051-0.

DOI:10.1016/0006-8993(85)91051-0
PMID:3986533
Abstract

Following injections of a wheat germ agglutinin-horseradish peroxidase (WGA-HRP) conjugate into representative areas of cerebellar cortex of tree shrew (Tupaia glis) retrogradely labeled cells were found in posterior, lateral and dorsal hypothalamic areas and in the lateral mammillary nucleus. These represent monosynaptic hypothalamocerebellar cortical projections. Anterogradely labeled axons were also traced into various areas of the contralateral hypothalamus subsequent to injections of WGA-HRP into the cerebellar nuclei. These results identify a direct cerebellar nucleohypothalamic pathway. These hypothalamocerebellar and cerebellohypothalamic connections represent potential circuits through which the cerebellum may interact with visceral centers.

摘要

将麦胚凝集素-辣根过氧化物酶(WGA-HRP)结合物注射到树鼩(Tupaia glis)小脑皮质的代表性区域后,在下丘脑后区、外侧区和背侧区以及外侧乳头核中发现了逆行标记的细胞。这些代表下丘脑-小脑皮质的单突触投射。在将WGA-HRP注射到小脑核团后,也追踪到了向对侧下丘脑各区域前行标记的轴突。这些结果确定了一条直接的小脑核团-下丘脑通路。这些下丘脑-小脑和小脑-下丘脑连接代表了小脑可能与内脏中枢相互作用的潜在回路。

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