Roth Y, Kimhi Y, Edery H, Aharonson E, Priel Z
Brain Res. 1985 Mar 25;330(2):291-7. doi: 10.1016/0006-8993(85)90688-2.
Ciliary beat frequency (CBF) in various parts of brain ventricular system, as well as in trachea of hamsters, was examined. Coronal sections of brain and tracheal rings were maintained in a thermostatically controlled perfusion chamber and CBF measured by a photoelectric system equipped with a fiber-optic probe. CBF (Hz) values of lateral ventricle, aqueduct and fourth ventricle were 27.9 +/- 4.6; 30.7 +/- 7.7 and 31.9 +/- 7.8 Hz, respectively. CBF in the third ventricle--19.8 +/- 7.1 Hz--was significantly lower than in other segments of ventricular system. CBF in choroid plexus cilia was very slow, 5-10 Hz, whereas in tracheal rings amounted to 13.7 +/- 3.1 Hz. Bovine cervical mucus and mucus stimulant reversibly inhibited CBF in brain but not in trachea. Brain cilia in contrast to those in trachea were not capable of transporting particles. In addition to demonstrating differences between tracheal and ependymal cilia, this work suggests that cilial motility plays a functional role in local mixing of cerebrospinal fluid, but does not relate to the bulk flow within the ventricular system.
研究了仓鼠脑室系统各部位以及气管的纤毛摆动频率（CBF）。将脑和气管环的冠状切片置于恒温控制的灌注室中，并用配备光纤探头的光电系统测量CBF。侧脑室、导水管和第四脑室的CBF（Hz）值分别为27.9±4.6；30.7±7.7和31.9±7.8Hz。第三脑室的CBF为19.8±7.1Hz，显著低于脑室系统的其他节段。脉络丛纤毛的CBF非常慢，为5 - 10Hz，而气管环的CBF为13.7±3.1Hz。牛宫颈黏液和黏液刺激剂可可逆地抑制脑内的CBF，但对气管无此作用。与气管纤毛不同，脑纤毛不能运输颗粒。除了证明气管纤毛和室管膜纤毛之间的差异外，这项研究还表明纤毛运动在脑脊液的局部混合中起功能性作用，但与脑室系统内的总体流动无关。
