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[子痫前期后持续性动脉高血压的流行病学及危险因素:在中乍友谊医院的一项纵向研究]

[Epidemiology and risk factors of persistent arterial hypertension after preeclampsia: a longitudinal study at the Chad-China Friendship Hospital].

作者信息

Langtar Mianroh Hybi, Allah-Amine Adjougoulta Koboy, Narcisse Dounè, Kiram Maimouna Djibrine, Tamoua Naibe Dangwe, Bachar Abakar, Igor Mbessoh Kengne Ulrich, Chene Mahamat Alhadji, Alsimbilaya Idriss Daraiya

机构信息

Service de Cardiologie de l'Hôpital de l'Amitié Tchad-Chine, Ndjamena, Tchad.

Service de Cardiologie, Centre Hospitalier Universitaire la Référence Nationale, Ndjamena, Tchad.

出版信息

Pan Afr Med J. 2024 Oct 18;49:44. doi: 10.11604/pamj.2024.49.44.43783. eCollection 2024.

Abstract

INTRODUCTION

arterial hypertension (AH) may persist beyond three months postpartum after preeclampsia, increasing the long-term risk of cardiovascular complications. The purpose of this study is to describe the epidemiological aspects and factors associated with persistent hypertension following preeclampsia.

METHODS

we conducted a longitudinal descriptive study, from January 2022 to June 2023. The study included patients who were hospitalized for preeclampsia in the maternity ward of the Chad-China Friendship Hospital and followed in the cardiology outpatient clinic for at least three months. A multivariate analysis using binary logistic regression was performed to identify factors associated with persistent hypertension.

RESULTS

during our study period, 144 patients were hospitalized for preeclampsia, of whom 92 were included in the study. The average age of patients was 26.32 ±7.05 years, with extremes ranging from 16 to 42 years. Multiparity was observed in 41.3% (n=38) of patients and severe preeclampsia occurred in 80.4% (n=74). Additionally, 17.4% (n=16) had twin pregnancies and obesity was found in 19.6% (n=18). Persistent arterial hypertension was present in 24 patients, representing a prevalence of 26.10% (n=24). A personal history of preeclampsia was the only factor significantly associated with persistent arterial hypertension (adjusted OR 5.30, 95% CI 1.31-21.44, p=0.01).

CONCLUSION

it is necessary to develop a care pathway for patients who have had preeclampsia in order to prevent and manage long-term complications at an early stage.

摘要

引言

子痫前期后动脉高血压(AH)可能在产后持续超过三个月,增加了心血管并发症的长期风险。本研究的目的是描述子痫前期后持续性高血压的流行病学特征及相关因素。

方法

我们于2022年1月至2023年6月进行了一项纵向描述性研究。该研究纳入了在中乍友谊医院产科病房因子痫前期住院,并在心脏病门诊随访至少三个月的患者。采用二元逻辑回归进行多变量分析,以确定与持续性高血压相关的因素。

结果

在我们的研究期间,144例患者因子痫前期住院,其中92例纳入研究。患者的平均年龄为26.32±7.05岁,年龄范围为16至42岁。41.3%(n = 38)的患者为经产妇,80.4%(n = 74)发生严重子痫前期。此外,17.4%(n = 16)为双胎妊娠,19.6%(n = 18)存在肥胖。24例患者存在持续性动脉高血压,患病率为26.10%(n = 24)。子痫前期个人史是与持续性动脉高血压显著相关的唯一因素(调整后的比值比为5.30,95%置信区间为1.31 - 21.44,p = 0.01)。

结论

有必要为子痫前期患者制定护理路径,以便早期预防和管理长期并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9fb/11760206/30e964ce31ce/PAMJ-49-44-g001.jpg

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