Viviani G, Cordera R, Odetti P, Corsi L, De Micheli A, Maiello M, Berri F, Prando R
Boll Soc Ital Biol Sper. 1979 Jun 30;55(11):1104-10.
The insulin response of 10 lean and 23 obese subjects with lag-type and borderline O.G.T.T. has been studied. The O.G.T.T. was interpreted according to the criteria of Fajans and Conn. The maximum increase and the area of increase were examined both for blood glucose and plasma I.R.I., and the corresponding I.R.I./glucose ratios calculated. The shape of the insulin response curve is similar to that of glucose curve. The I.R.I./glucose ratios are decreased in the lag-type curves as compared to borderline in the lean subjects while we observed opposite results in obese ones. A possible physiopathological interpretation of this curves is proposed.
对10名体型偏瘦和23名肥胖且患有迟发型和临界型口服葡萄糖耐量试验（O.G.T.T.）的受试者的胰岛素反应进行了研究。O.G.T.T. 根据法扬斯（Fajans）和康恩（Conn）的标准进行解读。对血糖和血浆胰岛素放射免疫活性（I.R.I.）的最大增加值和增加值面积进行了检查，并计算了相应的I.R.I./葡萄糖比值。胰岛素反应曲线的形状与葡萄糖曲线相似。与体型偏瘦受试者的临界型曲线相比，迟发型曲线中的I.R.I./葡萄糖比值降低，而在肥胖受试者中我们观察到了相反的结果。针对这些曲线提出了一种可能的生理病理学解释。
