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了解强直性脊柱炎脊柱手术的利弊:来自单机构研究的经验

Understanding the pros and cons of spine surgery for ankylosing spondylitis: experience from a single institution study.

作者信息

Chehrassan Mohammadreza, Shakeri Mohammadreza, Nikouei Farshad, Sabbaghan Saeed, Sour Behnam, Mahabadi Ebrahim Ameri, Ghandhari Hasan

机构信息

Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.

Department of Orthopedic Surgery, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Rheumatol. 2025 Jan 27;9(1):11. doi: 10.1186/s41927-025-00461-7.

DOI:10.1186/s41927-025-00461-7
PMID:39871320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11771011/
Abstract

INTRODUCTION

Ankylosing Spondylitis (AS) presents a complex inflammatory condition with significant impact on patients' lives. Despite advancements in understanding its pathogenesis, comprehensive elucidation remains elusive. This study investigates the outcomes of corrective spine surgery in AS patients, aiming to optimize management strategies.

METHODS

A retrospective cohort study was conducted, including 28 AS patients undergoing corrective surgery from 2016 to 2021. Surgical procedures primarily targeted realignment of the spine to alleviate deformities.

RESULTS

Radiological evaluations pre- and post-operatively revealed substantial improvements in sagittal balance and kyphosis correction. The mean correction of local kyphosis at the osteotomy site was 30.9 degrees. Minor surgical complications, though present, were managed effectively.

CONCLUSION

While acknowledging surgical complexities and potential complications, meticulous patient selection and appropriate techniques mitigate risks. This study emphasizes the pivotal role of surgical intervention in improving quality of life, particularly by addressing sagittal vertical axis and forward gaze disorders.

摘要

引言

强直性脊柱炎(AS)是一种复杂的炎症性疾病,对患者的生活有重大影响。尽管在理解其发病机制方面取得了进展,但全面阐明仍难以实现。本研究调查了AS患者脊柱矫正手术的结果,旨在优化管理策略。

方法

进行了一项回顾性队列研究,纳入了2016年至2021年期间接受矫正手术的28例AS患者。手术主要针对脊柱的重新排列以减轻畸形。

结果

术前和术后的影像学评估显示矢状面平衡和后凸矫正有显著改善。截骨部位局部后凸的平均矫正角度为30.9度。虽然存在轻微的手术并发症,但得到了有效处理。

结论

尽管认识到手术的复杂性和潜在并发症,但精心的患者选择和适当的技术可降低风险。本研究强调了手术干预在改善生活质量方面的关键作用,特别是通过解决矢状垂直轴和前视障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34df/11771011/33a32ae4a81c/41927_2025_461_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34df/11771011/10356e884755/41927_2025_461_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34df/11771011/33a32ae4a81c/41927_2025_461_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34df/11771011/10356e884755/41927_2025_461_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34df/11771011/33a32ae4a81c/41927_2025_461_Fig2_HTML.jpg

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本文引用的文献

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World Neurosurg. 2023 May;173:176-187.e1. doi: 10.1016/j.wneu.2023.01.101. Epub 2023 Feb 2.
2
Optimal immediate sagittal alignment for kyphosis in ankylosing spondylitis following corrective osteotomy.强直性脊柱炎截骨矫形术后驼背畸形矢状面的最佳即刻对线
Front Surg. 2022 Sep 5;9:975026. doi: 10.3389/fsurg.2022.975026. eCollection 2022.
3
Ankylosing spondylitis: an autoimmune or autoinflammatory disease?
强直性脊柱炎:一种自身免疫性疾病还是自身炎症性疾病?
Nat Rev Rheumatol. 2021 Jul;17(7):387-404. doi: 10.1038/s41584-021-00625-y. Epub 2021 Jun 10.
4
Improvement of Sleep Quality in Patients With Ankylosing Spondylitis Kyphosis After Corrective Surgery.强直性脊柱炎后凸畸形矫正术后患者睡眠质量的改善。
Spine (Phila Pa 1976). 2020 Dec 1;45(23):E1596-E1603. doi: 10.1097/BRS.0000000000003676.
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J Int Med Res. 2019 May;47(5):1877-1883. doi: 10.1177/0300060518811486. Epub 2019 Feb 7.
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