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肝包虫囊肿胆瘘的术前预测因素:单中心研究结果

Preoperative predictive factors of cystobiliary fistulas in liver hydatid cysts: results of a monocentric study.

作者信息

Jarrar Mohamed Salah, Karmani Ines, Chahed Mehdi, Barka Malek, Mraidha Mohamed Hedi, Toumi Radhouane, Beizig Ameni, Dhouioui Khayri, Youssef Sabri

机构信息

Department of General and Digestive Surgery, Farhat Hached University Hospital - Sousse, Sousse, Tunisia.

University of Sousse, Sousse, Tunisia.

出版信息

Future Sci OA. 2025 Dec;11(1):2458420. doi: 10.1080/20565623.2025.2458420. Epub 2025 Jan 27.

Abstract

INTRODUCTION

The evolution of hepatic hydatid cyst can be enameled with complications, mainly biliary fistula, which can be both symptomatic or occult. The aim of this study is to identify the predictive factors of occult cysto-biliary communication.

MATERIAL AND METHODS

This is a retrospective study of patients operated-on for uncomplicated hepatic hydatid cyst in Farhat Hached Hospital of Sousse over a period of 10 years.

RESULTS

Two hundred twenty patients were operated-on for uncomplicated hydatid cyst. In univariate analysis, alkaline-phosphatase, gamma-glutamyl-transferase, alanine-transferase elevated levels and multiple type were factors associated with occult fistula, but gamma-glutamyl-transferase level was the only predictor in multivariate analysis.

CONCLUSION

These predictive factors could contribute to determine preoperative probability of occult fistula, thus indicating additional intraoperative procedures to ensure its identification.

摘要

引言

肝包虫囊肿的演变可能伴有并发症,主要是胆瘘,其可能是有症状的或隐匿的。本研究的目的是确定隐匿性囊肿-胆管相通的预测因素。

材料与方法

这是一项对在苏塞法尔哈特·哈谢德医院接受单纯性肝包虫囊肿手术的患者进行的为期10年的回顾性研究。

结果

220例患者接受了单纯性包虫囊肿手术。单因素分析中,碱性磷酸酶、γ-谷氨酰转移酶、丙氨酸转移酶水平升高及囊肿多房型是与隐匿性瘘相关的因素,但多因素分析中γ-谷氨酰转移酶水平是唯一的预测因素。

结论

这些预测因素有助于确定隐匿性瘘的术前概率,从而提示额外的术中操作以确保其被识别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d500/11776849/a7fc7afb8085/IFSO_A_2458420_UF0001_C.jpg

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