Miao Ganggang, Zhang De, Li Jiajing, Deng Yanxiang, Gu Xingwei, Feng Tingting
Department of General Surgery, The People's Hospital of Danyang, Affiliated Danyang Hospital of Nantong University, Danyang, Jiangsu, China.
Department of General Surgery, The Affiliated Nanjing Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Front Oncol. 2025 Jan 13;14:1496074. doi: 10.3389/fonc.2024.1496074. eCollection 2024.
Gastric schwannoma is a relatively rare submucosal mesenchymal tumor with low probability of metastasis and arises from Schwann cells of the gastrointestinal nervous plexus. Surgical therapy is the main treatment of gastric schwannoma with symptoms or malignant tendency. Gastroparesis is a potential complication following gastrointestinal surgery, which is a clinical syndrome caused by gastric emptying disorder and characterized by nausea, vomiting, and bloating, resulting in insufficient nutrient intake. Generally, post-surgical etiology is the main potential etiology of gastroparesis, while the most common underlying etiology is diabetes mellitus. So far, reports of gastroparesis arising from resection of gastric schwannoma are rare. We present an 80-year-old woman who was diagnosed with gastrointestinal stromal tumor (GIST) primarily and has undergone laparoscopic wedge-shaped gastrectomy. The pathological and immunohistochemical examination ultimately established the diagnosis of gastric schwannoma. The patient experienced belching, nausea, vomiting, and bloating 1 week after the surgery and confirmed as gastroparesis through gastrointestinal series and gastroscopic examination. A series of treatments were performed, including correcting fluid-electrolyte disorders and vitamin deficiencies, and nutritional support and pharmacological treatments. The patient ultimately recovered well, and the relevant literatures were reviewed to identify and handle similar cases hereafter.
胃神经鞘瘤是一种相对罕见的黏膜下间质瘤,转移概率低,起源于胃肠神经丛的施万细胞。手术治疗是有症状或有恶变倾向的胃神经鞘瘤的主要治疗方法。胃轻瘫是胃肠手术后的一种潜在并发症,是由胃排空障碍引起的临床综合征,以恶心、呕吐和腹胀为特征,导致营养摄入不足。一般来说,手术后病因是胃轻瘫的主要潜在病因,而最常见的潜在病因是糖尿病。到目前为止,因胃神经鞘瘤切除引起胃轻瘫的报道很少。我们报告一例80岁女性患者,最初被诊断为胃肠道间质瘤(GIST),并接受了腹腔镜楔形胃切除术。病理及免疫组化检查最终确诊为胃神经鞘瘤。患者术后1周出现嗳气、恶心、呕吐和腹胀,经胃肠造影和胃镜检查确诊为胃轻瘫。进行了一系列治疗,包括纠正水电解质紊乱和维生素缺乏,以及营养支持和药物治疗。患者最终恢复良好,并查阅相关文献以识别和处理今后的类似病例。