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三孔胸腔镜手术肋间神经阻滞术后发生反弹痛的危险因素:一项病例对照研究

Risk Factors for the Occurrence of Rebound Pain After Intercostal Nerves Block in Three-Port Thoracoscopic Surgery: A Case-Control Study.

作者信息

Wan Chongyang, Kong Min, Shen Qihong, Lu Weina, Shen Xu

机构信息

Jiaxing University Master's Degree Cultivation Base, Zhejiang Chinese Medical University, Jiaxing City, Zhejiang Province, People's Republic of China.

Department of Anesthesiology and Pain Research Center, The Affiliated Hospital of Jiaxing University, Jiaxing City, Zhejiang Province, People's Republic of China.

出版信息

J Pain Res. 2025 Jan 23;18:381-390. doi: 10.2147/JPR.S494568. eCollection 2025.

Abstract

BACKGROUND AND OBJECTIVES

Rebound pain (RP), characterised by an acute increase in pain levels, is usually observed after the effects of block anaesthesia have subsided. Severe RP can cause adverse effects, thus affecting patient prognosis. In this study, we investigated the incidence of RP and its risk factors after intercostal nerve block in three-port thoracoscopic surgery to provide a clinical basis for identifying high-risk patients and providing early intervention.

METHODS

A single-centre retrospective study was conducted on 475 patients who underwent three-hole thoracoscopic surgery from September 2022 to September 2023 in Jiaxing First Hospital. Data were collected and compared between patients who developed RP and those who did not. IBM SPSS Statistics 25.0 software was used for statistical analysis.

RESULTS

Data were collected from 700 patients. After applying the exclusion criteria, 475 cases were finally included and the incidence of RP was 23.8%. The results showed that the differences in body mass index (BMI), upper and lower chest diameters, anterior and posterior chest diameters, left and right chest diameters, and gender between patients with RP and those without RP were statistically significant (p < 0.05). In addition, the proportion of female patients with RP was significantly higher. BMI (advantage ratio [OR] = 0.835, 95% confidence interval [CI]: 0.375 ~ 1.859), upper and lower chest diameters (OR = 0.916, 95% CI: 0.827 ~ 1.014), anterior and posterior chest diameters (OR = 0.765, 95% CI: 0.635 ~ 0.921), left and right chest diameters (OR = 0.612, 95% CI: 0.421 ~ 0.891), and gender (OR = 1.170, 95% CI: 0.576 ~ 2.373).

CONCLUSION

The incidence of RP after three-hole thoracoscopic intercostal nerve block is high and associated with multiple risk factors. Early intervention is needed for patients at risk of RP to improve patient prognosis and satisfaction.

摘要

背景与目的

反弹痛(RP)的特征是疼痛水平急剧增加,通常在局部麻醉效果消退后出现。严重的RP会导致不良反应,从而影响患者预后。在本研究中,我们调查了三孔胸腔镜手术中肋间神经阻滞后RP的发生率及其危险因素,为识别高危患者并提供早期干预提供临床依据。

方法

对2022年9月至2023年9月在嘉兴市第一医院接受三孔胸腔镜手术的475例患者进行单中心回顾性研究。收集发生RP的患者与未发生RP的患者的数据并进行比较。使用IBM SPSS Statistics 25.0软件进行统计分析。

结果

收集了700例患者的数据。应用排除标准后,最终纳入475例,RP发生率为23.8%。结果显示,发生RP的患者与未发生RP的患者在体重指数(BMI)、胸廓上下径、胸廓前后径、胸廓左右径以及性别方面的差异具有统计学意义(p<0.05)。此外,女性RP患者的比例显著更高。BMI(优势比[OR]=0.835,95%置信区间[CI]:0.3751.859)、胸廓上下径(OR=0.916,95%CI:0.8271.014)、胸廓前后径(OR=0.765,95%CI:0.6350.921)、胸廓左右径(OR=0.612,95%CI:0.4210.891)以及性别(OR=1.170,95%CI:0.576~2.373)。

结论

三孔胸腔镜肋间神经阻滞后RP的发生率较高,且与多种危险因素相关。对有RP风险的患者需要进行早期干预,以改善患者预后和满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca80/11771156/1bc1b355500e/JPR-18-381-g0001.jpg

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