病毒发病机制的分子成像及未来机遇。

Molecular imaging of viral pathogenesis and opportunities for the future.

作者信息

Kelly Brianna, Boudreau Jeanette E, Beyea Steven, Brewer Kimberly

机构信息

Biomedical MRI Research Laboratory (BMRL), IWK Health Centre, Halifax, NS Canada.

Department of Microbiology & Immunology, Dalhousie University, Halifax, NS Canada.

出版信息

Npj Imaging. 2025;3(1):3. doi: 10.1038/s44303-024-00056-w. Epub 2025 Jan 24.

DOI:10.1038/s44303-024-00056-w

PMID:39872292

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11761071/

Abstract

Molecular imaging is used in clinical and research settings. Since tools to study viral pathogenesis longitudinally and systemically are limited, molecular imaging is an attractive and largely unexplored tool. This review discusses molecular imaging probes and techniques for studying viruses, particularly those currently used in oncology that are applicable to virology. Expanding the repertoire of probes to better detect viral disease may make imaging even more valuable in (pre-)clinical settings.

摘要

分子成像应用于临床和研究领域。由于纵向和系统研究病毒发病机制的工具有限，分子成像是一种有吸引力且在很大程度上未被探索的工具。本文综述了用于研究病毒的分子成像探针和技术，特别是目前肿瘤学中使用的、适用于病毒学的那些。扩大探针种类以更好地检测病毒疾病可能会使成像在（预）临床环境中更具价值。