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Tuning mitochondrial dynamics for aging intervention.

作者信息

Yao Xudong, Xia Xiaojun, Hay David C, Shipston Mike, Ouyang Hongwei

机构信息

International School of Medicine, International Institutes of Medicine, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, Yiwu 322000, China.

Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, Department of Orthopedic Surgery of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.

出版信息

Life Med. 2024 Feb 8;3(1):lnae008. doi: 10.1093/lifemedi/lnae008. eCollection 2024 Feb.

DOI:10.1093/lifemedi/lnae008
PMID:39872392
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749249/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe0d/11749249/4b0fbd3d44fe/lnae008_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe0d/11749249/4b0fbd3d44fe/lnae008_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe0d/11749249/4b0fbd3d44fe/lnae008_fig1.jpg

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本文引用的文献

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Strand-selective base editing of human mitochondrial DNA using mitoBEs.使用 mitoBE 对人线粒体 DNA 进行链选择性碱基编辑。
Nat Biotechnol. 2024 Mar;42(3):498-509. doi: 10.1038/s41587-023-01791-y. Epub 2023 May 22.
2
Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction.通过靶向 DRP1-受体相互作用抑制线粒体分裂。
Cell Chem Biol. 2023 Mar 16;30(3):278-294.e11. doi: 10.1016/j.chembiol.2023.02.002. Epub 2023 Feb 23.
3
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction.
线粒体融合的小分子激动剂可修复线粒体功能障碍。
Nat Chem Biol. 2023 Apr;19(4):468-477. doi: 10.1038/s41589-022-01224-y. Epub 2023 Jan 12.
4
Modulating mitofusins to control mitochondrial function and signaling.调节线粒体融合蛋白以控制线粒体功能和信号转导。
Nat Commun. 2022 Jul 7;13(1):3775. doi: 10.1038/s41467-022-31324-1.
5
Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression.线粒体分裂通过降低 MHC-I 表面表达在实体瘤中诱导免疫逃逸。
Nat Commun. 2022 Jul 6;13(1):3882. doi: 10.1038/s41467-022-31417-x.
6
Mitochondria transplantation between living cells.活细胞之间的线粒体移植。
PLoS Biol. 2022 Mar 23;20(3):e3001576. doi: 10.1371/journal.pbio.3001576. eCollection 2022 Mar.
7
In-cytoplasm mitochondrial transplantation for mesenchymal stem cells engineering and tissue regeneration.用于间充质干细胞工程和组织再生的胞质内线粒体移植
Bioeng Transl Med. 2021 Sep 28;7(1):e10250. doi: 10.1002/btm2.10250. eCollection 2022 Jan.
8
Supramolecular Antagonists Promote Mitochondrial Dysfunction.超分子拮抗剂促进线粒体功能障碍。
Nano Lett. 2021 Jul 14;21(13):5730-5737. doi: 10.1021/acs.nanolett.1c01469. Epub 2021 Jun 18.
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Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity.小分子通过靶向 CK2 而不影响其常规激酶活性诱导线粒体融合以实现神经保护。
Signal Transduct Target Ther. 2021 Feb 19;6(1):71. doi: 10.1038/s41392-020-00447-6.
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Supramolecular Induction of Mitochondrial Aggregation and Fusion.超分子诱导的线粒体聚集与融合。
J Am Chem Soc. 2020 Sep 30;142(39):16523-16527. doi: 10.1021/jacs.0c06783. Epub 2020 Sep 1.