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迪拜体外生命支持在术中心脏骤停的开创性应用:一例报告

Pioneering Use of Extracorporeal Life Support in Intraoperative Cardiac Arrest in Dubai: A Case Report.

作者信息

Kotsev Strahil N, Nour Nadine B, Allah Dad Muhammad Sharif

机构信息

Department of Anaesthesia and Intensive Care, Latifa Hospital, Dubai Health, Dubai, ARE.

出版信息

Cureus. 2024 Dec 28;16(12):e76523. doi: 10.7759/cureus.76523. eCollection 2024 Dec.

Abstract

We describe, to our knowledge, the first use in Dubai of extracorporeal life support (ECLS) in a patient who suffered intraoperative cardiac arrest due to presumed cardiac channelopathy. A 40-year-old patient presented for open myomectomy surgery. She had no other medical problems apart from obesity. The patient denied any family history of surgery or anesthesia-related complications. Her initial electrocardiogram (ECG) and laboratory results were within reference limits. Intraoperatively, the patient suffered sudden cardiac arrest, from which she was resuscitated. Point-of-care cardiac ultrasound and intensive care unit (ICU)-performed echocardiography revealed severely reduced left ventricular contractility. Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and intra-aortic balloon pump were utilized in the immediate postoperative period. Although the patient's heart sustained more than 300 DC shocks, it recovered. Family members revealed that the patient's brother and sister had died in their 20s from sudden cardiac death. Another sister had been resuscitated a few years ago from intraoperative cardiac arrest, too. The case illustrates the importance of the patient's disclosure of relevant information. It supports the notion that ECLS can be used in the immediate postoperative period if surgical hemostasis is achieved. Controversies, such as the use of heparinization and the risk of bleeding, transthoracic echocardiography (TTE) versus transesophageal echocardiography (TEE), timely insertion of intracardiac defibrillator, and genetic screening, are discussed. A learning point is that clinicians do not work in a vacuum. Organizational leadership can greatly impact outcomes, creating conditions for safer patient care.

摘要

据我们所知,我们描述了迪拜首例在因疑似心脏离子通道病而术中发生心脏骤停的患者中使用体外生命支持(ECLS)的情况。一名40岁患者因开放性子宫肌瘤切除术入院。除肥胖外,她没有其他健康问题。患者否认有任何手术或麻醉相关并发症的家族史。她最初的心电图(ECG)和实验室检查结果均在参考范围内。术中,患者突然发生心脏骤停,后经复苏成功。床旁心脏超声和重症监护病房(ICU)进行的超声心动图显示左心室收缩力严重下降。术后即刻使用了静脉-动脉体外膜肺氧合(V-A ECMO)和主动脉内球囊泵。尽管患者心脏接受了超过300次直流电除颤,但仍恢复了。家属透露,患者的哥哥和姐姐在20多岁时死于心源性猝死。另一个姐姐几年前也曾在术中发生心脏骤停后复苏成功。该病例说明了患者披露相关信息的重要性。它支持这样一种观点,即如果实现了手术止血,ECLS可在术后即刻使用。文中还讨论了一些争议问题,如肝素化的使用和出血风险、经胸超声心动图(TTE)与经食管超声心动图(TEE)的比较、心脏除颤器的及时植入以及基因筛查等。一个经验教训是,临床医生并非在真空中工作。组织领导能力会对治疗结果产生重大影响,为更安全的患者护理创造条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de2/11772079/452dcf013950/cureus-0016-00000076523-i01.jpg

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