Kazim Samrana, Haris M P U, Ahmad Shahzada
Materials Physics Center, CSIC-UPV/EHU, Paseo Manuel de Lardizabal 5, Donostia-San Sebastian, 20018, Spain.
BCMaterials, Basque Center for Materials, Applications, and Nanostructures, UPV/EHU Science Park, Leioa, 48940, Spain.
Adv Sci (Weinh). 2025 Mar;12(9):e2408919. doi: 10.1002/advs.202408919. Epub 2025 Jan 28.
The growing demand for environmentally friendly semiconductors that can be tailored and developed easily is compelling researchers and technologists to design inherently bio-compatible, self-assembling nanostructures with tunable semiconducting characteristics. Peptide-based bioinspired materials exhibit a variety of supramolecular morphologies and have the potential to function as organic semiconductors. Such biologically or naturally derived peptides with intrinsic semiconducting characteristics create new opportunities for sustainable biomolecule-based optoelectronics devices. Affably, halide perovskite nanocrystals are emerging as potentially attractive nano-electronic analogs, in this vein creating synergies and probing peptide-perovskite-based bio-electronics are of paramount interest. The physical properties and inherent aromatic short-peptide assemblies that can stabilize, and passivate the defects at surfaces assist in improving the charge transport in halide perovskite devices. This review sheds light on how these peptide-perovskite nano-assemblies can be developed for optical sensing, optoelectronics, and imaging for biomedical and healthcare applications. The charge transfer mechanism in peptides along with as an outlook the electron transfer mechanism between perovskite and short peptide chains, which is paramount to facilitate their entry into molecular electronics is discussed. Future aspects, prevailing challenges, and research directions in the field of perovskite-peptides are also presented.
对易于定制和开发的环保型半导体的需求不断增长，促使研究人员和技术专家设计具有固有生物相容性、可自组装且具有可调半导体特性的纳米结构。基于肽的仿生材料展现出多种超分子形态，并有潜力用作有机半导体。这类具有内在半导体特性的生物源或天然衍生肽为可持续的基于生物分子的光电器件创造了新机遇。同样，卤化物钙钛矿纳米晶体正成为潜在有吸引力的纳米电子类似物，因此，探索基于肽 - 钙钛矿的生物电子学并创造协同效应至关重要。能够稳定并钝化表面缺陷的物理性质和固有芳香短肽组装体有助于改善卤化物钙钛矿器件中的电荷传输。本综述阐明了如何开发这些肽 - 钙钛矿纳米组装体用于生物医学和医疗保健应用中的光学传感、光电子学及成像。讨论了肽中的电荷转移机制以及作为展望的钙钛矿与短肽链之间的电子转移机制，这对于促进它们进入分子电子学至关重要。还介绍了钙钛矿 - 肽领域的未来发展方向、当前面临的挑战及研究方向。
