Seçkin Göbüt Özden, Sezenöz Burak, Küçükbardaslı Muhammet, Yamak Betül Ayça, Ünlü Serkan
Cardiology Department, Gazi University Hospital, Yenimahalle, Ankara, Turkey.
Echocardiography. 2025 Feb;42(2):e70056. doi: 10.1111/echo.70056.
Idiopathic right bundle branch block (RBBB) is often seen as harmless and common. However, many studies show it might be linked to negative health outcomes. So, it is crucial to fully understand how RBBB affects the heart's ventricles.
This study aims to examine the right and left ventricular systolic functions in patients with idiopathic RBBB and compare them to those in a healthy control group.
Echocardiographic images were obtained from patients with idiopathic RBBB and healthy control participants. Conventional echocardiographic parameters were measured. Two-dimensional (2D) speckle tracking strain analysis was used to assess deformation indices.
Thirty-nine patients with idiopathic RBBB and 35 healthy participants were included in the study. There were no significant differences in the chamber dimensions of the left ventricle (LV) and right ventricle (RV) between the groups. LV ejection fraction (EF), RV fractional area change (FAC), and tricuspid annular plane systolic excursion (TAPSE) measurements were similar between the groups. LV global longitudinal strain (GLS) (-25.5 ± 5.7% vs. -22.1 ± 4.2%, p < 0.05), RV GLS (-26.9 ± 4.6% vs. -24.0 ± 4.4%, p < 0.05), and interventricular septum longitudinal strain (IVS LS) (-24.3 ± 4.9% vs. -19.1 ± 4.2%, p < 0.05) were significantly reduced in patients with idiopathic RBBB compared to controls, indicating impaired myocardial shortening. Significant differences were also observed in LV (15 [5-30] vs. 30 [20-60], p < 0.05) and RV (18 [7-35] vs. 36 [24-80], p < 0.05) mechanical dispersion, with the differences being more pronounced for the RV between the groups. LV torsion (2.1 ± 0.6 vs. 1.6 ± 0.5, p < 0.05) was also worse in patients with idiopathic RBBB.
Our findings show that idiopathic RBBB significantly affects the longitudinal strain and synchronization of both the LV and RV.
特发性右束支传导阻滞（RBBB）常被视为无害且常见。然而，许多研究表明它可能与不良健康结果有关。因此，充分了解RBBB如何影响心脏心室至关重要。
本研究旨在检查特发性RBBB患者的右心室和左心室收缩功能，并将其与健康对照组进行比较。
从特发性RBBB患者和健康对照参与者处获取超声心动图图像。测量常规超声心动图参数。使用二维（2D）斑点追踪应变分析来评估变形指数。
本研究纳入了39例特发性RBBB患者和35名健康参与者。两组之间左心室（LV）和右心室（RV）的腔室尺寸无显著差异。两组之间的左心室射血分数（EF）、右心室面积变化分数（FAC）和三尖瓣环平面收缩期位移（TAPSE）测量值相似。与对照组相比，特发性RBBB患者的左心室整体纵向应变（GLS）（-25.5±5.7%对-22.1±4.2%，p<0.05）、右心室GLS（-26.9±4.6%对-24.0±4.4%，p<0.05）和室间隔纵向应变（IVS LS）（-24.3±4.9%对-19.1±4.2%，p<0.05）显著降低，表明心肌缩短受损。在左心室（15[5-30]对30[20-60]，p<0.05）和右心室（18[7-35]对36[24-80]，p<0.05）的机械离散方面也观察到显著差异，两组之间右心室的差异更为明显。特发性RBBB患者的左心室扭转（2.1±0.6对1.6±0.5，p<0.05）也更严重。
我们的研究结果表明，特发性RBBB显著影响左心室和右心室的纵向应变及同步性。
