Chen Yuxiang, Zhu Xinrui, Ding Shasha, Chen Mo, Yang Jinlin, Deng Kai
Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China; Sichuan University-Oxford University Huaxi Gastrointestinal Cancer Centre, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Department of Gerontology, Tibetan Chengdu Branch Hospital of West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China; Department of Gerontology, Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Chengdu, 610041, China.
Eur J Surg Oncol. 2025 May;51(5):109626. doi: 10.1016/j.ejso.2025.109626. Epub 2025 Jan 22.
The increasing detection of submucosal tumors (SMTs) in the upper gastrointestinal tract (UGI) is due to the increased clinical use of endoscopy and imaging technology. Some of these SMTs have malignant potential and may cause clinical symptoms. Thus, it is recommended in clinical guidelines to consider resection of these SMTs. Endoscopic techniques have become widely used in the diagnosis and treatment of SMT in the UGI as compared with traditional surgery due to their advantages of minimally invasive, quick recovery, and economical cost. Recently, new endoscopic techniques and instruments have been continuously implemented, leading to revolutionary innovation in endoscopic treatments. However, the safety and efficacy of these innovative techniques remain unclear. Therefore, we have comprehensively summarized the various techniques used in the treatment of UGI tumors in recent years, evaluated the indications and effects of each technique, and compared their benefits and disadvantages. We hope that this review will provide a more comprehensive reference for clinical and endoscopic practitioners, and help them develop more individualized treatment plans for different patients. This will ultimately expand the patient population that can benefit from these innovative technologies.
上消化道（UGI）黏膜下肿瘤（SMTs）检出率的增加归因于内镜检查和成像技术在临床上的更多应用。其中一些SMTs具有恶变潜能，可能会引起临床症状。因此，临床指南建议考虑切除这些SMTs。与传统手术相比，内镜技术因其微创、恢复快和成本低的优点，已广泛应用于UGI中SMT的诊断和治疗。近年来，新的内镜技术和器械不断涌现，带来了内镜治疗的革命性创新。然而，这些创新技术的安全性和有效性仍不明确。因此，我们全面总结了近年来用于治疗UGI肿瘤的各种技术，评估了每种技术的适应症和效果，并比较了它们的优缺点。我们希望这篇综述能为临床和内镜从业者提供更全面的参考，并帮助他们为不同患者制定更个性化的治疗方案。这最终将扩大受益于这些创新技术的患者群体。
