Lan Fangfang, Jiang Kuihong
Surgery for external hand wound reconstruction, Lishui People's Hospital, Lishui, China.
Z Orthop Unfall. 2025 Jun;163(3):241-249. doi: 10.1055/a-2504-4538. Epub 2025 Jan 28.
Hip fractures (HFs) are common in elderly patients and are associated with high mortality rates and functional impairment. Malnutrition has been shown to negatively impact postoperative survival rates in HF patients. However, the relationship between the Geriatric Nutrition Risk Index (GNRI) and the risk of HF remains unclear. This study aims to evaluate the association between GNRI and HF risk, with a particular focus on the elderly male population.We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) for the periods 2007-2010, 2013-2014, and 2017-2018. Through multivariate regression analysis, we assessed the association between GNRI and HF and performed stratified and subgroup analyses to further explore this relationship. Additionally, we utilized restricted cubic splines (RCSs) to investigate the potential nonlinear relationship between GNRI and HF risk.The study found that gender significantly influenced the relationship between GNRI and HF (p for interaction = 0.002). In males, GNRI was significantly negatively associated with the risk of HF (OR < 1, p < 0.05). RCS analysis showed that the relationship between GNRI and HF risk in elderly males might be linearly negative. The critical threshold for GNRI was identified as 104.14, beyond which the risk of HF significantly decreased.This study demonstrates a linear negative correlation between GNRI and the risk of HF in elderly males, with a GNRI of 104.14 identified as the critical threshold for predicting the risk of hip fractures.
髋部骨折(HFs)在老年患者中很常见,且与高死亡率和功能障碍相关。营养不良已被证明会对髋部骨折患者的术后生存率产生负面影响。然而,老年营养风险指数(GNRI)与髋部骨折风险之间的关系仍不清楚。本研究旨在评估GNRI与髋部骨折风险之间的关联,特别关注老年男性人群。
我们使用了2007 - 2010年、2013 - 2014年和2017 - 2018年国家健康与营养检查调查(NHANES)的数据进行了一项横断面研究。通过多变量回归分析,我们评估了GNRI与髋部骨折之间的关联,并进行了分层和亚组分析以进一步探讨这种关系。此外,我们使用限制立方样条(RCSs)来研究GNRI与髋部骨折风险之间潜在的非线性关系。
研究发现,性别对GNRI与髋部骨折之间的关系有显著影响(交互作用p = 0.002)。在男性中,GNRI与髋部骨折风险显著负相关(OR < 1,p < 0.05)。RCS分析表明,老年男性中GNRI与髋部骨折风险之间的关系可能呈线性负相关。GNRI的临界阈值被确定为104.14,超过该值髋部骨折风险显著降低。
本研究表明老年男性中GNRI与髋部骨折风险之间存在线性负相关,GNRI为104.14被确定为预测髋部骨折风险的临界阈值。