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青少年期出现的先天性脊柱侧弯:未行半椎体切除术的治疗结果

Congenital scoliosis presenting in teenage years outcomes without hemivertebra excision.

作者信息

Sarwahi Vishal, Hasan Sayyida, Visahan Keshin, Rahman Effat, Eigo Katherine, Galina Jesse, Goldstein Jeffrey, Dowling Thomas J, Fakhoury Jordan, Lo Yungtai, Amaral Terry

机构信息

Department of Orthopaedics, Spinal Deformity and Pediatric Orthopaedics, Billie and George Ross Center for Advanced Pediatric Orthopaedics and Minimally Invasive Spinal Surgery, Cohen Children's Medical Center, Northwell Hofstra School of Medicine, 7 Vermont Drive, Lake Success, NY, 11042, USA.

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Spine Deform. 2025 May;13(3):835-843. doi: 10.1007/s43390-025-01039-6. Epub 2025 Jan 29.

DOI:10.1007/s43390-025-01039-6
PMID:39875733
Abstract

PURPOSE

In congenital scoliosis, the surgical strategy approach of hemivertebra excision, with or without instrumentation and fusion, is a common approach to correction of scoliosis. However, hemivertebra excisions are technically challenging, with potential complications including spinal cord injury, nerve root injury and cerebrospinal fluid leak. The purpose of this study was to determine whether correction of congenital scoliosis can be achieved using a posterior instrumentation/fusion-only approach without the need for hemivertebra excision.

METHODS

35 patients with congenital scoliosis and hemivertebra operated between 2007 and 2024 were matched to 35 AIS patients by BMI, levels fused, and preoperative Cobb. Wilcoxon rank-sum tests, chi-square tests, and Fisher's Exact tests were utilized.

RESULTS

Age (p = 0.22), BMI (p = 0.25) and preoperative Cobb (p = 0.79) were similar between hemivertebra and AIS patients. Cobb correction (HV: 71.8% vs. AIS: 70.4%; p = 0.92) and EBL (500 cc vs. 400 cc; p = 1.0) were similar. Operative time (310.0 min vs. 242.0 min; p < 0.001) and length of stay (7.0 days vs. 5.0 days; p < 0.001) were statistically different. Patients operated on after 2018, when the Rapid Recovery Protocol was implemented, had a similar length of stay (4.5 vs. 5.0; p = 0.92). Patients in both cohorts had similar SRS-22 scores.

CONCLUSION

Choosing fusion levels in congenital patients, on similar principles to AIS, leads to avoidance of hemivertebra excision, including lumbosacral hemivertebrae. This approach is safer than hemivertebra excision and has similar, or better, curve correction than previously reported.

摘要

目的

在先天性脊柱侧凸中,半椎体切除的手术策略方法,无论是否进行内固定和融合,都是矫正脊柱侧凸的常用方法。然而,半椎体切除在技术上具有挑战性,潜在并发症包括脊髓损伤、神经根损伤和脑脊液漏。本研究的目的是确定是否可以通过仅后路内固定/融合方法来实现先天性脊柱侧凸的矫正,而无需进行半椎体切除。

方法

对2007年至2024年间接受手术的35例先天性脊柱侧凸伴半椎体患者,按照体重指数(BMI)、融合节段和术前Cobb角与35例特发性脊柱侧凸(AIS)患者进行匹配。采用Wilcoxon秩和检验、卡方检验和Fisher精确检验。

结果

半椎体患者与AIS患者在年龄(p = 0.22)、BMI(p = 0.25)和术前Cobb角(p = 0.79)方面相似。Cobb角矫正率(半椎体组:71.8% vs. AIS组:70.4%;p = 0.92)和估计失血量(EBL)(500 cc vs. 400 cc;p = 1.0)相似。手术时间(310.0分钟 vs. 242.0分钟;p < 0.001)和住院时间(7.0天 vs. 5.0天;p < 0.001)有统计学差异。在2018年实施快速康复方案后接受手术的患者住院时间相似(4.5天 vs. 5.0天;p = 0.92)。两组患者的脊柱侧凸研究学会(SRS-22)评分相似。

结论

按照与AIS相似的原则选择先天性患者的融合节段,可避免半椎体切除,包括腰骶部半椎体。这种方法比半椎体切除更安全,并且具有与先前报道相似或更好的曲线矫正效果。

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本文引用的文献

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Selection of Fusion Levels in Adolescent Idiopathic Scoliosis.青少年特发性脊柱侧凸融合节段的选择
Curr Rev Musculoskelet Med. 2024 Jan;17(1):23-36. doi: 10.1007/s12178-023-09876-6. Epub 2023 Dec 14.
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Hemivertebra Resection in Small Children. A Literature Review.小儿半椎体切除术:文献综述
Global Spine J. 2023 Apr;13(3):897-909. doi: 10.1177/21925682221130060. Epub 2022 Sep 27.
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A Newer Way of Determining LIV in AIS Patients: Rotation of the Touched Vertebrae.一种新的确定 AIS 患者 LIV 的方法:触诊椎体的旋转。
Spine (Phila Pa 1976). 2022 Sep 15;47(18):1321-1327. doi: 10.1097/BRS.0000000000004378. Epub 2022 Jul 28.
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Scoliosis Surgery Normalizes Cardiac Function in Adolescent Idiopathic Scoliosis Patients.脊柱侧弯矫形手术可使青少年特发性脊柱侧弯患者的心脏功能恢复正常。
Spine (Phila Pa 1976). 2021 Nov 1;46(21):E1161-E1167. doi: 10.1097/BRS.0000000000004060.
5
Selecting the "Touched Vertebra" as the Lowest Instrumented Vertebra in Patients with Lenke Type-1 and 2 Curves: Radiographic Results After a Minimum 5-Year Follow-up.选择“触诊椎体”作为 Lenke 型 1 和 2 型曲线患者的最低置钉椎体:至少 5 年随访的影像学结果。
J Bone Joint Surg Am. 2020 Nov 18;102(22):1966-1973. doi: 10.2106/JBJS.19.01485.
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Clinical Characteristics and Risk Factors of Recurrent Lumbar Disk Herniation: A Retrospective Analysis of Three Hundred Twenty-One Cases.临床特点与复发性腰椎间盘突出症的危险因素:三百二十一例回顾性分析。
Spine (Phila Pa 1976). 2018 Nov 1;43(21):1463-1469. doi: 10.1097/BRS.0000000000002655.
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Radiological and clinical outcome of selective thoracic fusion for patients with Lenke 1C and 2C adolescent idiopathic scoliosis with a minimum follow-up of 2 years.选择性胸椎融合治疗 Lenke 1C 和 2C 型青少年特发性脊柱侧凸的影像学和临床结果:至少 2 年的随访。
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The Results of Hemivertebra Resection by the Posterior Approach in Children with a Mean Follow-Up of Five Years.儿童后路半椎体切除术的结果:平均五年随访
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Surgical Site Infection in Adolescent Idiopathic Scoliosis Surgery.青少年特发性脊柱侧弯手术中的手术部位感染
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Ponte osteotomies to treat major thoracic adolescent idiopathic scoliosis curves allow more effective corrective maneuvers.采用椎弓根截骨术治疗青少年重度胸椎特发性脊柱侧凸曲线可实现更有效的矫正操作。
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