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世界卫生组织在12个国家开展的关于核医学成像设备质量性能的实验室间比对研究。

World health organisation inter-laboratory comparison study in 12 countries on quality performance of nuclear medicine imaging devices.

作者信息

Volodin V, Souchkevitch G, Racoveanu N, Bergmann H, Busemann-Sokole E, Delaloye B, Dermentzoglou F, Georgescu G, Herrera N, Jasinski W

出版信息

Eur J Nucl Med. 1985;10(5-6):193-7. doi: 10.1007/BF00254460.

DOI:10.1007/BF00254460
PMID:3987697
Abstract

Twelve countries participated in the WHO intercomparison for which transmission CAP (College of American Pathologists) brain and CAP liver phantoms and emission London liver phantoms were used. A total of 157 imaging devices were tested. Overall results from the phantoms revealed a wide range of targets detected. For the CAP-phantoms target detectability dropped below 50% for target sizes less than 9 mm and below 60% for target contrast less than 0.84:1. On average one false positive and six false negative results were reported using CAP-brain phantoms and one false positive and one false negative result using CAP-liver phantoms. For the London liver phantoms containing the tissue equivalent rubber abdominal simulation the target of 1 cm was never visualised. Two targets in this phantom (2 cm and 2.5 cm) were correctly identified in 34% of studies and one of these targets in 52% of studies. Equivocal and false positive results were reported in 42%. The WHO inter-comparison demonstrated the need to establish new, or to improve the existing, quality control programmes.

摘要

12个国家参与了世界卫生组织的比对研究,该研究使用了美国病理学家学会(CAP)的脑部和肝脏体模以及伦敦发射型肝脏体模。总共测试了157台成像设备。体模的总体结果显示检测到的目标范围很广。对于CAP体模,当目标尺寸小于9毫米时,目标可检测性降至50%以下,当目标对比度小于0.84:1时,目标可检测性降至60%以下。使用CAP脑部体模平均报告1例假阳性和6例假阴性结果,使用CAP肝脏体模平均报告1例假阳性和1例假阴性结果。对于包含组织等效橡胶腹部模拟的伦敦肝脏体模,1厘米的目标从未被观察到。该体模中的两个目标(2厘米和2.5厘米)在34%的研究中被正确识别,其中一个目标在52%的研究中被正确识别。42%的研究报告了模棱两可和假阳性结果。世界卫生组织的比对研究表明有必要建立新的或改进现有的质量控制计划。

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本文引用的文献

1
The London liver phantom.伦敦肝脏体模。
J Nucl Med. 1983 Oct;24(10):974-5.
Eur J Nucl Med. 1990;16(1):23-8. doi: 10.1007/BF01566008.