Hermann G A, Herrera N E, Hauser W
Am J Clin Pathol. 1980 Oct;74(4 Suppl):591-4.
Twelve sets of emission phantoms were distributed semiannually to laboratories of nuclear medicine from 1973 through 1978. This survey aimed to create a national peer group within which it might become possible to compare and standardize nuclear imaging technics, and to evaluate and define the current state of the art in a clinical setting. Results were analyzed in terms of sensitivity (percentage of true-positives), nonspecificity (percentage of false-positives), and performance indices (true-positive/false-negative ratios) for conventional gamma cameras and for rectilinear scanners. The chief determinants of target detectability proved to be target-to-surface depth, target diameter, and intrinsic target contrast. Operational variables and instrument type produced relatively minor effect upon subscriber performance. Gamma cameras tended to show slightly more sensitivity than rectilinear scanners, but were somewhat troubled by nonspecificity. Improvements in the intrinsic resolution of second- and third-generation gamma cameras increasingly employed since 1975 showed negligible impact on performance indices. A consideration of the overall survey performance indices. A consideration of the overall survey performance permits the beginning of a quantitative estimate of current detection capability in day-to-day nuclear imaging.
从1973年到1978年，每半年向核医学实验室分发12套发射型体模。这项调查旨在创建一个全国性的同行群体，在此群体中有可能对核成像技术进行比较和标准化，并在临床环境中评估和界定当前的技术水平。针对传统伽马相机和直线扫描仪，根据灵敏度（真阳性百分比）、非特异性（假阳性百分比）和性能指标（真阳性/假阴性比率）对结果进行了分析。结果表明，目标可探测性的主要决定因素是目标到体表的深度、目标直径和目标固有对比度。操作变量和仪器类型对用户的性能产生的影响相对较小。伽马相机的灵敏度往往比直线扫描仪略高，但在非特异性方面存在一些问题。自1975年以来越来越多地使用的第二代和第三代伽马相机，其固有分辨率的提高对性能指标的影响微乎其微。对总体调查性能指标的考虑。对总体调查性能的考虑使得能够开始对日常核成像中的当前检测能力进行定量估计。
