Bódis J, Zámbó K, Nemessányi Z, Máté E, Csaba I F
Eur J Nucl Med. 1985;10(5-6):286-7. doi: 10.1007/BF00254477.
We developed a new radioisotope technique to measure placental blood flow for the early detection of placental insufficiency. Using the parametric scan, placental perfusion was measured in 80 late-pregnant women. The T-maximum pictures obtained made it possible to differentiate between the vascular and intervillous phases of placental blood flow. The time period of intervillous phase calculated as the percentage of the whole placental Tmax was given as the intervillous perfusion index (IPI). It was demonstrated that the IPI was significantly higher in pregnancies complicated with intrauterine growth retardation (64.2% +/- 16.5%), hypertension (60.0 +/- 15.2) and oedema (57.9% +/- 10.1%) than in the control group (33.7% +/- 10.5%). These data suggest that the first sign of placental insufficiency is the prolongation of the IPI which is likely to precede the quantitative reduction of placental perfusion.
我们开发了一种新的放射性同位素技术来测量胎盘血流，以便早期发现胎盘功能不全。通过参数扫描，对80名晚期孕妇的胎盘灌注情况进行了测量。所获得的最大时间（T-max）图像使得区分胎盘血流的血管期和绒毛间隙期成为可能。将绒毛间隙期的时间段计算为整个胎盘Tmax的百分比，作为绒毛间隙灌注指数（IPI）。结果表明，与对照组（33.7%±10.5%）相比，患有宫内生长迟缓（64.2%±16.5%）、高血压（60.0±15.2）和水肿（57.9%±10.1%）的孕妇的IPI显著更高。这些数据表明，胎盘功能不全的首要迹象是IPI延长，这可能先于胎盘灌注的定量减少。
