Goldwasser B, Sarig S, Azoury R, Orda S, Boichis H, Wax Y, Many M
Eur Urol. 1985;11(1):40-3. doi: 10.1159/000472447.
In the present study it has been found that hyperuricosuric calcium oxalate (CaOx) stone formers do not differ from idiopathic CaOx stone formers in their urines' potential to retard in vitro precipitation of CaOx. On the other hand, urines of hyperuricosuric patients with no history of CaOx stone formation have the same potential to inhibit CaOx precipitation as those of normal controls. Reduction of urinary uric acid concentrations by either incubation of specimens with sodium urate or by treatment of hyperuricosuric patients with allopurinol had no effect on the urines' potential to retard CaOx precipitation.
在本研究中发现，高尿酸尿草酸钙（CaOx）结石形成者的尿液抑制CaOx体外沉淀的能力与特发性CaOx结石形成者并无差异。另一方面，无CaOx结石形成病史的高尿酸尿患者的尿液抑制CaOx沉淀的能力与正常对照者相同。通过用尿酸钠孵育标本或用别嘌呤醇治疗高尿酸尿患者来降低尿尿酸浓度，对尿液抑制CaOx沉淀的能力没有影响。
