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一名日本患者因[具体病因未给出]导致腹股沟区尿道皮肤瘘和皮下脓肿伴菌血症:病例报告。

Urethrocutaneous fistula and subcutaneous abscess in the inguinal region with bacteremia caused by in a Japanese patient: A case report.

作者信息

Furuya Kento, Itoh Naoya

机构信息

Division of Infection Control and Prevention, Shizuoka General Hospital, Shizuoka, Japan.

Department of Internal Medicine, Izu Redcross Hospital, Shizuoka, Japan.

出版信息

IDCases. 2025 Jan 7;39:e02147. doi: 10.1016/j.idcr.2025.e02147. eCollection 2025.

DOI:10.1016/j.idcr.2025.e02147
PMID:39877720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11773272/
Abstract

is an anaerobic, gram-negative bacillus commonly associated with acute appendicitis. However, bacteremia is exceedingly rare. Herein, we report a case of bacteremia associated with a urethrocutaneous fistula and a subcutaneous abscess in the left inguinal region. A 75-year-old man was referred to our hospital due to persistent fever despite piperacillin treatment. The patient was diagnosed with a urethrocutaneous fistula and a subcutaneous abscess in the left inguinal region. was isolated from his blood culture and identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Subsequently, the patient underwent a four-week course of piperacillin-tazobactam therapy. Since a susceptibility breakpoint has not been established for , standardized treatment guidelines are currently unavailable. This case represents the first successful treatment of bacteremia with piperacillin-tazobactam, suggesting it may be an effective therapeutic option for infections caused by .

摘要

是一种厌氧菌,革兰氏阴性杆菌,通常与急性阑尾炎有关。然而,菌血症极为罕见。在此,我们报告一例与尿道皮肤瘘和左腹股沟区皮下脓肿相关的菌血症病例。一名75岁男性因哌拉西林治疗后仍持续发热被转诊至我院。患者被诊断为左腹股沟区尿道皮肤瘘和皮下脓肿。从他的血培养中分离出该菌,并通过基质辅助激光解吸电离飞行时间质谱法进行鉴定。随后,患者接受了为期四周的哌拉西林 - 他唑巴坦治疗。由于尚未确定该菌的药敏折点,目前尚无标准化治疗指南。该病例代表了首例用哌拉西林 - 他唑巴坦成功治疗该菌菌血症的案例,表明它可能是由该菌引起的感染的有效治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/aa9ee6897bc9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/c91b6a7fb1c8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/9a9b39f868fc/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/aa9ee6897bc9/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/c91b6a7fb1c8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/9a9b39f868fc/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d061/11773272/aa9ee6897bc9/gr3.jpg

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Anaerobe. 2022 Dec;78:102641. doi: 10.1016/j.anaerobe.2022.102641. Epub 2022 Sep 13.
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Anaerobic bacteraemia: a 10-year retrospective epidemiological survey.厌氧菌血症:一项为期10年的回顾性流行病学调查。
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